Metagenomic Next-Generation Sequencing for the Diagnosis of Epstein-Barr virus Pleurisy: A Case Report

Chronic active Epstein-Barr virus infection (CAEBV) progresses rapidly in the later stage and has a poor prognosis. The treatments of CAEBV have no unified standard and a bad effect. Only few person could cure. It is important to diagnosis early. Metagenomic next-generation sequencing (mNGS) offers...

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Autores principales: Hui Lv, JIn Liu, Ruoyu Zhang
Formato: article
Lenguaje:EN
Publicado: Tehran University of Medical Sciences 2021
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Acceso en línea:https://doaj.org/article/abb4da9c5b884153a8e811cf423e53be
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Sumario:Chronic active Epstein-Barr virus infection (CAEBV) progresses rapidly in the later stage and has a poor prognosis. The treatments of CAEBV have no unified standard and a bad effect. Only few person could cure. It is important to diagnosis early. Metagenomic next-generation sequencing (mNGS) offers an effective means for the diagnosis of difficult, critical and rare pathogenic microbial infections. Here, we report a case of viral pleurisy caused by CAEBV identified by mNGS in an 88-year-old Chinese male patient.