Origins of Transcriptional Transition: Balance between Upstream and Downstream Regulatory Gene Sequences

ABSTRACT By measuring individual mRNA production at the single-cell level, we investigated the lac promoter’s transcriptional transition during cell growth phases. In exponential phase, variation in transition rates generates two mixed phenotypes, low and high numbers of mRNAs, by modulating their b...

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Autores principales: Adrien Sala, Muhammad Shoaib, Olga Anufrieva, Gnanavel Mutharasu, Olli Yli-Harja, Meenakshisundaram Kandhavelu
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2015
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Acceso en línea:https://doaj.org/article/abb6d2e7498d4d989e193838b8ef6b47
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