Origins of Transcriptional Transition: Balance between Upstream and Downstream Regulatory Gene Sequences

ABSTRACT By measuring individual mRNA production at the single-cell level, we investigated the lac promoter’s transcriptional transition during cell growth phases. In exponential phase, variation in transition rates generates two mixed phenotypes, low and high numbers of mRNAs, by modulating their b...

Full description

Saved in:
Bibliographic Details
Main Authors: Adrien Sala, Muhammad Shoaib, Olga Anufrieva, Gnanavel Mutharasu, Olli Yli-Harja, Meenakshisundaram Kandhavelu
Format: article
Language:EN
Published: American Society for Microbiology 2015
Subjects:
Online Access:https://doaj.org/article/abb6d2e7498d4d989e193838b8ef6b47
Tags: Add Tag
No Tags, Be the first to tag this record!