Model-based prediction of spatial gene expression via generative linear mapping
Single cell RNA-seq loses spatial information of gene expression in multicellular systems because tissue must be dissociated. Here, the authors show the spatial gene expression profiles can be both accurately and robustly reconstructed by a new computational method using a generative linear mapping,...
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Main Authors: | Yasushi Okochi, Shunta Sakaguchi, Ken Nakae, Takefumi Kondo, Honda Naoki |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Subjects: | |
Online Access: | https://doaj.org/article/abbd231b7f69497dae153503ce587d0f |
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