Model-based prediction of spatial gene expression via generative linear mapping

Single cell RNA-seq loses spatial information of gene expression in multicellular systems because tissue must be dissociated. Here, the authors show the spatial gene expression profiles can be both accurately and robustly reconstructed by a new computational method using a generative linear mapping,...

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Auteurs principaux: Yasushi Okochi, Shunta Sakaguchi, Ken Nakae, Takefumi Kondo, Honda Naoki
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/abbd231b7f69497dae153503ce587d0f
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