Human lactate dehydrogenase a inhibitors: a molecular dynamics investigation.

Lactate dehydrogenase A (LDHA) is an important enzyme in fermentative glycolysis, generating most energy for cancer cells that rely on anaerobic respiration even under normal oxygen concentrations. This renders LDHA a promising molecular target for the treatment of various cancers. Several efforts h...

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Autores principales: Yun Shi, B Mario Pinto
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/abca69299a7246b0a79a3495c68266eb
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