Synergistic effect of tumor chemo-immunotherapy induced by leukocyte-hitchhiking thermal-sensitive micelles

Targeting the adenosinergic pathway represents a therapeutic option to overcome tumor-induced immunosuppression. Here the authors design E-selectin-modified thermal-sensitive micelles loaded with doxorubicin and an adenosine A2 receptor antagonist to enhance chemotherapy-induced anti-tumor immune re...

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Autores principales:	Jing Qi, Feiyang Jin, Yuchan You, Yan Du, Di Liu, Xiaoling Xu, Jun Wang, Luwen Zhu, Minjiang Chen, Gaofeng Shu, Liming Wu, Jiansong Ji, Yongzhong Du
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/abce4ae1a7124d5ebad9a32c2e0500b4
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:abce4ae1a7124d5ebad9a32c2e0500b4
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spelling	oai:doaj.org-article:abce4ae1a7124d5ebad9a32c2e0500b42021-12-02T18:49:22ZSynergistic effect of tumor chemo-immunotherapy induced by leukocyte-hitchhiking thermal-sensitive micelles10.1038/s41467-021-24902-22041-1723https://doaj.org/article/abce4ae1a7124d5ebad9a32c2e0500b42021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24902-2https://doaj.org/toc/2041-1723Targeting the adenosinergic pathway represents a therapeutic option to overcome tumor-induced immunosuppression. Here the authors design E-selectin-modified thermal-sensitive micelles loaded with doxorubicin and an adenosine A2 receptor antagonist to enhance chemotherapy-induced anti-tumor immune responses.Jing QiFeiyang JinYuchan YouYan DuDi LiuXiaoling XuJun WangLuwen ZhuMinjiang ChenGaofeng ShuLiming WuJiansong JiYongzhong DuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jing Qi Feiyang Jin Yuchan You Yan Du Di Liu Xiaoling Xu Jun Wang Luwen Zhu Minjiang Chen Gaofeng Shu Liming Wu Jiansong Ji Yongzhong Du Synergistic effect of tumor chemo-immunotherapy induced by leukocyte-hitchhiking thermal-sensitive micelles
description	Targeting the adenosinergic pathway represents a therapeutic option to overcome tumor-induced immunosuppression. Here the authors design E-selectin-modified thermal-sensitive micelles loaded with doxorubicin and an adenosine A2 receptor antagonist to enhance chemotherapy-induced anti-tumor immune responses.
format	article
author	Jing Qi Feiyang Jin Yuchan You Yan Du Di Liu Xiaoling Xu Jun Wang Luwen Zhu Minjiang Chen Gaofeng Shu Liming Wu Jiansong Ji Yongzhong Du
author_facet	Jing Qi Feiyang Jin Yuchan You Yan Du Di Liu Xiaoling Xu Jun Wang Luwen Zhu Minjiang Chen Gaofeng Shu Liming Wu Jiansong Ji Yongzhong Du
author_sort	Jing Qi
title	Synergistic effect of tumor chemo-immunotherapy induced by leukocyte-hitchhiking thermal-sensitive micelles
title_short	Synergistic effect of tumor chemo-immunotherapy induced by leukocyte-hitchhiking thermal-sensitive micelles
title_full	Synergistic effect of tumor chemo-immunotherapy induced by leukocyte-hitchhiking thermal-sensitive micelles
title_fullStr	Synergistic effect of tumor chemo-immunotherapy induced by leukocyte-hitchhiking thermal-sensitive micelles
title_full_unstemmed	Synergistic effect of tumor chemo-immunotherapy induced by leukocyte-hitchhiking thermal-sensitive micelles
title_sort	synergistic effect of tumor chemo-immunotherapy induced by leukocyte-hitchhiking thermal-sensitive micelles
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/abce4ae1a7124d5ebad9a32c2e0500b4
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Synergistic effect of tumor chemo-immunotherapy induced by leukocyte-hitchhiking thermal-sensitive micelles

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