COMPARISON OF STEROIDS TO NSAIDS, AND OTHER FORMS OF ANALGESIA IN THE MANAGEMENT OF POST-CHIKUNGUNYA ARTHRITIS

Objective: To compare steroids with other treatment options like NSAIDS and other analgesics for management of postchikungunya arthritis based on visual analogue scale (VAS). Study Design: Comparative cross-sectional study. Place and Duration of Study: Department of Rheumatology, Liaquat Natio...

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Autores principales:	Hamza Alam, Tahira Perveen Umer, Iffat Khanum, Lubna Nazir, Uzma Erum, Muhammad Irfan
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2021
Materias:	chikungunya viral fever post-chikungunya arthritis post-infectious arthritis Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/abd096e38fc3474a9e8f8c6b6b12e2ff
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spelling	oai:doaj.org-article:abd096e38fc3474a9e8f8c6b6b12e2ff2021-12-02T18:44:47ZCOMPARISON OF STEROIDS TO NSAIDS, AND OTHER FORMS OF ANALGESIA IN THE MANAGEMENT OF POST-CHIKUNGUNYA ARTHRITIS0030-96482411-884210.51253/pafmj.v71i2.2712https://doaj.org/article/abd096e38fc3474a9e8f8c6b6b12e2ff2021-04-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/2712https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To compare steroids with other treatment options like NSAIDS and other analgesics for management of postchikungunya arthritis based on visual analogue scale (VAS). Study Design: Comparative cross-sectional study. Place and Duration of Study: Department of Rheumatology, Liaquat National Hospital, Karachi, from Jan to Jul 2018. Methodology: A total of 112 patients were included in this study, of both genders. Patients with history of fever >38.5°C and polyarthralgia who had positive chikungunya IgM serology or PCR were included in this study. Patients fulfilling inclusion criteria and who were treatment naïve were given NSAIDs or other analgesics if contraindication to NSAIDs was present. Those who had received 2 weeks of NSAIDs were given a single dose of intramuscular steroids. Response to treatment was characterized by clinical examination according to visual analogue scale (VAS) taken at baseline, 2 weeks and 4 weeks. All analyses will be conducted by using SPSS-20. Results: Overall, 66 (58.9%) received steroids, 37 (33%) patients were given NSAIDs, and other forms of analgesics were prescribed to 9 (8%) patients. In nearly half of the patients, i.e. 57 (50.89%) partial response was seen, 13 (11.6%) showed complete response, while 42 (37.5%) had persistent arthralgia, which was statistically significant p-value <0.001. Conclusion: This study shows that improvement in symptoms is seen with a single dose of intra-muscular steroid and it helped bring down the VAS score.Hamza AlamTahira Perveen UmerIffat KhanumLubna NazirUzma ErumMuhammad IrfanArmy Medical College Rawalpindiarticlechikungunya viral feverpost-chikungunya arthritispost-infectious arthritisMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 71, Iss 2, Pp 619-24 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	chikungunya viral fever post-chikungunya arthritis post-infectious arthritis Medicine R Medicine (General) R5-920
spellingShingle	chikungunya viral fever post-chikungunya arthritis post-infectious arthritis Medicine R Medicine (General) R5-920 Hamza Alam Tahira Perveen Umer Iffat Khanum Lubna Nazir Uzma Erum Muhammad Irfan COMPARISON OF STEROIDS TO NSAIDS, AND OTHER FORMS OF ANALGESIA IN THE MANAGEMENT OF POST-CHIKUNGUNYA ARTHRITIS
description	Objective: To compare steroids with other treatment options like NSAIDS and other analgesics for management of postchikungunya arthritis based on visual analogue scale (VAS). Study Design: Comparative cross-sectional study. Place and Duration of Study: Department of Rheumatology, Liaquat National Hospital, Karachi, from Jan to Jul 2018. Methodology: A total of 112 patients were included in this study, of both genders. Patients with history of fever >38.5°C and polyarthralgia who had positive chikungunya IgM serology or PCR were included in this study. Patients fulfilling inclusion criteria and who were treatment naïve were given NSAIDs or other analgesics if contraindication to NSAIDs was present. Those who had received 2 weeks of NSAIDs were given a single dose of intramuscular steroids. Response to treatment was characterized by clinical examination according to visual analogue scale (VAS) taken at baseline, 2 weeks and 4 weeks. All analyses will be conducted by using SPSS-20. Results: Overall, 66 (58.9%) received steroids, 37 (33%) patients were given NSAIDs, and other forms of analgesics were prescribed to 9 (8%) patients. In nearly half of the patients, i.e. 57 (50.89%) partial response was seen, 13 (11.6%) showed complete response, while 42 (37.5%) had persistent arthralgia, which was statistically significant p-value <0.001. Conclusion: This study shows that improvement in symptoms is seen with a single dose of intra-muscular steroid and it helped bring down the VAS score.
format	article
author	Hamza Alam Tahira Perveen Umer Iffat Khanum Lubna Nazir Uzma Erum Muhammad Irfan
author_facet	Hamza Alam Tahira Perveen Umer Iffat Khanum Lubna Nazir Uzma Erum Muhammad Irfan
author_sort	Hamza Alam
title	COMPARISON OF STEROIDS TO NSAIDS, AND OTHER FORMS OF ANALGESIA IN THE MANAGEMENT OF POST-CHIKUNGUNYA ARTHRITIS
title_short	COMPARISON OF STEROIDS TO NSAIDS, AND OTHER FORMS OF ANALGESIA IN THE MANAGEMENT OF POST-CHIKUNGUNYA ARTHRITIS
title_full	COMPARISON OF STEROIDS TO NSAIDS, AND OTHER FORMS OF ANALGESIA IN THE MANAGEMENT OF POST-CHIKUNGUNYA ARTHRITIS
title_fullStr	COMPARISON OF STEROIDS TO NSAIDS, AND OTHER FORMS OF ANALGESIA IN THE MANAGEMENT OF POST-CHIKUNGUNYA ARTHRITIS
title_full_unstemmed	COMPARISON OF STEROIDS TO NSAIDS, AND OTHER FORMS OF ANALGESIA IN THE MANAGEMENT OF POST-CHIKUNGUNYA ARTHRITIS
title_sort	comparison of steroids to nsaids, and other forms of analgesia in the management of post-chikungunya arthritis
publisher	Army Medical College Rawalpindi
publishDate	2021
url	https://doaj.org/article/abd096e38fc3474a9e8f8c6b6b12e2ff
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COMPARISON OF STEROIDS TO NSAIDS, AND OTHER FORMS OF ANALGESIA IN THE MANAGEMENT OF POST-CHIKUNGUNYA ARTHRITIS

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