Timely regulated sorting from early to late endosomes is required to maintain cerebellar long-term depression

Long term depression (LTD) of the cerebellum is known to be mediated by postsynaptic trafficking of glutamate receptor AMPAR. Here, Kim and colleagues show that early- to late-endosomal sorting of AMPAR represents the switch from expression to maintenance phase of cerebellar LTD.

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Autores principales:	Taegon Kim, Yukio Yamamoto, Keiko Tanaka-Yamamoto
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/abd2334d67f54e4fa0ad7d89a0ff7206
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spelling	oai:doaj.org-article:abd2334d67f54e4fa0ad7d89a0ff72062021-12-02T17:06:09ZTimely regulated sorting from early to late endosomes is required to maintain cerebellar long-term depression10.1038/s41467-017-00518-32041-1723https://doaj.org/article/abd2334d67f54e4fa0ad7d89a0ff72062017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00518-3https://doaj.org/toc/2041-1723Long term depression (LTD) of the cerebellum is known to be mediated by postsynaptic trafficking of glutamate receptor AMPAR. Here, Kim and colleagues show that early- to late-endosomal sorting of AMPAR represents the switch from expression to maintenance phase of cerebellar LTD.Taegon KimYukio YamamotoKeiko Tanaka-YamamotoNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Taegon Kim Yukio Yamamoto Keiko Tanaka-Yamamoto Timely regulated sorting from early to late endosomes is required to maintain cerebellar long-term depression
description	Long term depression (LTD) of the cerebellum is known to be mediated by postsynaptic trafficking of glutamate receptor AMPAR. Here, Kim and colleagues show that early- to late-endosomal sorting of AMPAR represents the switch from expression to maintenance phase of cerebellar LTD.
format	article
author	Taegon Kim Yukio Yamamoto Keiko Tanaka-Yamamoto
author_facet	Taegon Kim Yukio Yamamoto Keiko Tanaka-Yamamoto
author_sort	Taegon Kim
title	Timely regulated sorting from early to late endosomes is required to maintain cerebellar long-term depression
title_short	Timely regulated sorting from early to late endosomes is required to maintain cerebellar long-term depression
title_full	Timely regulated sorting from early to late endosomes is required to maintain cerebellar long-term depression
title_fullStr	Timely regulated sorting from early to late endosomes is required to maintain cerebellar long-term depression
title_full_unstemmed	Timely regulated sorting from early to late endosomes is required to maintain cerebellar long-term depression
title_sort	timely regulated sorting from early to late endosomes is required to maintain cerebellar long-term depression
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/abd2334d67f54e4fa0ad7d89a0ff7206
work_keys_str_mv	AT taegonkim timelyregulatedsortingfromearlytolateendosomesisrequiredtomaintaincerebellarlongtermdepression AT yukioyamamoto timelyregulatedsortingfromearlytolateendosomesisrequiredtomaintaincerebellarlongtermdepression AT keikotanakayamamoto timelyregulatedsortingfromearlytolateendosomesisrequiredtomaintaincerebellarlongtermdepression
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Timely regulated sorting from early to late endosomes is required to maintain cerebellar long-term depression

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