Timely regulated sorting from early to late endosomes is required to maintain cerebellar long-term depression
Long term depression (LTD) of the cerebellum is known to be mediated by postsynaptic trafficking of glutamate receptor AMPAR. Here, Kim and colleagues show that early- to late-endosomal sorting of AMPAR represents the switch from expression to maintenance phase of cerebellar LTD.
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Auteurs principaux: | Taegon Kim, Yukio Yamamoto, Keiko Tanaka-Yamamoto |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
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Sujets: | |
Accès en ligne: | https://doaj.org/article/abd2334d67f54e4fa0ad7d89a0ff7206 |
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