New Insight into Filamentous Hemagglutinin Secretion Reveals a Role for Full-Length FhaB in <italic toggle="yes">Bordetella</italic> Virulence
ABSTRACT Bordetella filamentous hemagglutinin (FHA), a primary component of acellular pertussis vaccines, contributes to virulence, but how it functions mechanistically is unclear. FHA is first synthesized as an ~370-kDa preproprotein called FhaB. Removal of an N-terminal signal peptide and a large...
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Auteurs principaux: | Jeffrey A. Melvin, Erich V. Scheller, Christopher R. Noël, Peggy A. Cotter |
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Format: | article |
Langue: | EN |
Publié: |
American Society for Microbiology
2015
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Accès en ligne: | https://doaj.org/article/abdb820fc385442cb40926f0005786cc |
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