New-generation filler based on cross-linked carboxymethylcellulose: study of 350 patients with 3-year follow-up

Mauro Leonardis,1 Andrea Palange2 1Department of Plastic Surgery, Salvator Mundi International Hospital, 2Department of Aesthetic Medicine, Fisiobios Clinic, Rome, Italy Purpose: In recent years there has been a growing interest in nonsurgical procedures for facial rejuvenation. Hyaluronic acid is...

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Autores principales:	Leonardis M, Palange A
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	dermal fillers nasolabial fold hyaluronic acids facial aging patient satisfaction. Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/abe5578c991448f99640d9dccfe26161
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spelling	oai:doaj.org-article:abe5578c991448f99640d9dccfe261612021-12-02T00:33:12ZNew-generation filler based on cross-linked carboxymethylcellulose: study of 350 patients with 3-year follow-up1178-1998https://doaj.org/article/abe5578c991448f99640d9dccfe261612015-01-01T00:00:00Zhttps://www.dovepress.com/new-generation-filler-based-on-cross-linked-carboxymethylcellulose-stu-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Mauro Leonardis,1 Andrea Palange2 1Department of Plastic Surgery, Salvator Mundi International Hospital, 2Department of Aesthetic Medicine, Fisiobios Clinic, Rome, Italy Purpose: In recent years there has been a growing interest in nonsurgical procedures for facial rejuvenation. Hyaluronic acid is currently the most widely used dermal filler for the treatment of facial wrinkles. However, new products with interesting features are being introduced into the market. Cross-linked carboxymethylcellulose is one of these and represents a new alternative for the correction of wrinkles and facial defects.Patients and methods: The retrospective, multicenter, open-label study on nasolabial folds reported here was carried out between January 2010 and April 2014 on 350 subjects between 22 and 67 years of age for a 36-month follow-up period in order to consistently and extensively assess the safety and performance of this treatment.Results: The study revealed effective and durable correction of nasolabial wrinkles for periods of 9–12 months. Product reapplication over a 36-month period did not lead to an increase in adverse effects, which always remained rare and of little clinical significance, usually consisting of bruising and redness.Conclusion: Cross-linked carboxymethyl cellulose has been shown to be a safe and effective alternative to the resorbable products currently on the market. Keywords: dermal fillers, nasolabial fold, hyaluronic acids, facial aging, patient satisfactionLeonardis MPalange ADove Medical Pressarticledermal fillersnasolabial foldhyaluronic acidsfacial agingpatient satisfaction.GeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 10, Pp 147-155 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	dermal fillers nasolabial fold hyaluronic acids facial aging patient satisfaction. Geriatrics RC952-954.6
spellingShingle	dermal fillers nasolabial fold hyaluronic acids facial aging patient satisfaction. Geriatrics RC952-954.6 Leonardis M Palange A New-generation filler based on cross-linked carboxymethylcellulose: study of 350 patients with 3-year follow-up
description	Mauro Leonardis,1 Andrea Palange2 1Department of Plastic Surgery, Salvator Mundi International Hospital, 2Department of Aesthetic Medicine, Fisiobios Clinic, Rome, Italy Purpose: In recent years there has been a growing interest in nonsurgical procedures for facial rejuvenation. Hyaluronic acid is currently the most widely used dermal filler for the treatment of facial wrinkles. However, new products with interesting features are being introduced into the market. Cross-linked carboxymethylcellulose is one of these and represents a new alternative for the correction of wrinkles and facial defects.Patients and methods: The retrospective, multicenter, open-label study on nasolabial folds reported here was carried out between January 2010 and April 2014 on 350 subjects between 22 and 67 years of age for a 36-month follow-up period in order to consistently and extensively assess the safety and performance of this treatment.Results: The study revealed effective and durable correction of nasolabial wrinkles for periods of 9–12 months. Product reapplication over a 36-month period did not lead to an increase in adverse effects, which always remained rare and of little clinical significance, usually consisting of bruising and redness.Conclusion: Cross-linked carboxymethyl cellulose has been shown to be a safe and effective alternative to the resorbable products currently on the market. Keywords: dermal fillers, nasolabial fold, hyaluronic acids, facial aging, patient satisfaction
format	article
author	Leonardis M Palange A
author_facet	Leonardis M Palange A
author_sort	Leonardis M
title	New-generation filler based on cross-linked carboxymethylcellulose: study of 350 patients with 3-year follow-up
title_short	New-generation filler based on cross-linked carboxymethylcellulose: study of 350 patients with 3-year follow-up
title_full	New-generation filler based on cross-linked carboxymethylcellulose: study of 350 patients with 3-year follow-up
title_fullStr	New-generation filler based on cross-linked carboxymethylcellulose: study of 350 patients with 3-year follow-up
title_full_unstemmed	New-generation filler based on cross-linked carboxymethylcellulose: study of 350 patients with 3-year follow-up
title_sort	new-generation filler based on cross-linked carboxymethylcellulose: study of 350 patients with 3-year follow-up
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/abe5578c991448f99640d9dccfe26161
work_keys_str_mv	AT leonardism newgenerationfillerbasedoncrosslinkedcarboxymethylcellulosestudyof350patientswith3yearfollowup AT palangea newgenerationfillerbasedoncrosslinkedcarboxymethylcellulosestudyof350patientswith3yearfollowup
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New-generation filler based on cross-linked carboxymethylcellulose: study of 350 patients with 3-year follow-up

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