Assessment of Cardiovascular Risk Factors in Patients with Type 2 Diabetes in Upper Egypt Villages

Ahmed Hussein,1 Sharaf ED Mahmoud,1 Mohammad Shafiq Awad,2 Hossam Eldin M Mahmoud3 1Department of Internal Medicine, Faculty of Medicine, Sohag University, Nasser City, Sohag 82524, Egypt; 2Department of Cardiology, Faculty of Medicine, Beni Suef University, Beni Suef City 62511, Egypt; 3Department...

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Autores principales:	Hussein A, Mahmoud SED, Awad MS, Mahmoud HEM
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	dm hba1c cv risk factors cvd. Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/abe5e36981cb45be8b0fdeaceda3c5d9
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spelling	oai:doaj.org-article:abe5e36981cb45be8b0fdeaceda3c5d92021-12-02T11:52:51ZAssessment of Cardiovascular Risk Factors in Patients with Type 2 Diabetes in Upper Egypt Villages1178-7007https://doaj.org/article/abe5e36981cb45be8b0fdeaceda3c5d92020-12-01T00:00:00Zhttps://www.dovepress.com/assessment-of-cardiovascular-risk-factors-in-patients-with-type-2-diab-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Ahmed Hussein,1 Sharaf ED Mahmoud,1 Mohammad Shafiq Awad,2 Hossam Eldin M Mahmoud3 1Department of Internal Medicine, Faculty of Medicine, Sohag University, Nasser City, Sohag 82524, Egypt; 2Department of Cardiology, Faculty of Medicine, Beni Suef University, Beni Suef City 62511, Egypt; 3Department of Internal Medicine, Faculty of Medicine, South Valley University, Qena City 83511, EgyptCorrespondence: Ahmed HusseinDepartment of Internal Medicine, Faculty of Medicine, Sohag University, Nasser City, Sohag 82524, EgyptTel +20 1011145537Fax +20 934600349Email ahmed_hussien@med.sohag.edu.egBackground: A large percentage of diabetic patients also have other components of metabolic syndrome, which is a group of cardiovascular (CV) hazard factors related to both diabetes mellitus (DM) and cardiovascular diseases (CVD). We do not know about the prevalence of CV risk factors in diabetic patients in Upper Egypt. We aimed to assess the CV risk factors in type 2 diabetic patients in Upper Egypt villages.Methods: We conducted a cross-sectional study that included 800 patients with type 2 DM. We classified the participants into three groups according to the hemoglobin A1c (HbA1c) levels. We assessed the prevalence of other cardiovascular risk factors and their association with HbA1c levels through a detailed history, full clinical examination, and laboratory tests.Results: We found that 75% of the participants were males, 25.5% elderly, 60.25% had hypertension, 60.75% had dyslipidemia, 33.25% were overweight or obese, 19.75% had a family history of coronary artery disease (CAD), 55.75% had established CVD, 42.5% were smokers, and only 12.25% were physically inactive. We found that 84% of the participants had ≥ two cardiovascular risk factors other than DM. HbA1c level was ≥ 7% in 77% of patients. After multivariate regression analysis, we found a significant association of higher systolic blood pressure (BP), more elevated diastolic BP, higher body mass index (BMI), increased waist circumference, old age, long duration of DM, and an increase in the number of clustered CV risk factors with a higher HbA1c level. At the same time, insulin therapy was significantly associated with a lower HbA1c level.Conclusion: All type 2 diabetic patients in Upper Egypt villages have other associated CV risk factors. The clustering of cardiovascular risk factors showed a significant association with higher HbA1c levels. These findings require the thought of associated CV risk factors in choosing medical treatments to optimize glycemic control and multifactorial intervention to improve CV risk.Keywords: DM, HbA1c, CV risk factors, CVDHussein AMahmoud SEDAwad MSMahmoud HEMDove Medical Pressarticledmhba1ccv risk factorscvd.Specialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 13, Pp 4737-4746 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	dm hba1c cv risk factors cvd. Specialties of internal medicine RC581-951
spellingShingle	dm hba1c cv risk factors cvd. Specialties of internal medicine RC581-951 Hussein A Mahmoud SED Awad MS Mahmoud HEM Assessment of Cardiovascular Risk Factors in Patients with Type 2 Diabetes in Upper Egypt Villages
description	Ahmed Hussein,1 Sharaf ED Mahmoud,1 Mohammad Shafiq Awad,2 Hossam Eldin M Mahmoud3 1Department of Internal Medicine, Faculty of Medicine, Sohag University, Nasser City, Sohag 82524, Egypt; 2Department of Cardiology, Faculty of Medicine, Beni Suef University, Beni Suef City 62511, Egypt; 3Department of Internal Medicine, Faculty of Medicine, South Valley University, Qena City 83511, EgyptCorrespondence: Ahmed HusseinDepartment of Internal Medicine, Faculty of Medicine, Sohag University, Nasser City, Sohag 82524, EgyptTel +20 1011145537Fax +20 934600349Email ahmed_hussien@med.sohag.edu.egBackground: A large percentage of diabetic patients also have other components of metabolic syndrome, which is a group of cardiovascular (CV) hazard factors related to both diabetes mellitus (DM) and cardiovascular diseases (CVD). We do not know about the prevalence of CV risk factors in diabetic patients in Upper Egypt. We aimed to assess the CV risk factors in type 2 diabetic patients in Upper Egypt villages.Methods: We conducted a cross-sectional study that included 800 patients with type 2 DM. We classified the participants into three groups according to the hemoglobin A1c (HbA1c) levels. We assessed the prevalence of other cardiovascular risk factors and their association with HbA1c levels through a detailed history, full clinical examination, and laboratory tests.Results: We found that 75% of the participants were males, 25.5% elderly, 60.25% had hypertension, 60.75% had dyslipidemia, 33.25% were overweight or obese, 19.75% had a family history of coronary artery disease (CAD), 55.75% had established CVD, 42.5% were smokers, and only 12.25% were physically inactive. We found that 84% of the participants had ≥ two cardiovascular risk factors other than DM. HbA1c level was ≥ 7% in 77% of patients. After multivariate regression analysis, we found a significant association of higher systolic blood pressure (BP), more elevated diastolic BP, higher body mass index (BMI), increased waist circumference, old age, long duration of DM, and an increase in the number of clustered CV risk factors with a higher HbA1c level. At the same time, insulin therapy was significantly associated with a lower HbA1c level.Conclusion: All type 2 diabetic patients in Upper Egypt villages have other associated CV risk factors. The clustering of cardiovascular risk factors showed a significant association with higher HbA1c levels. These findings require the thought of associated CV risk factors in choosing medical treatments to optimize glycemic control and multifactorial intervention to improve CV risk.Keywords: DM, HbA1c, CV risk factors, CVD
format	article
author	Hussein A Mahmoud SED Awad MS Mahmoud HEM
author_facet	Hussein A Mahmoud SED Awad MS Mahmoud HEM
author_sort	Hussein A
title	Assessment of Cardiovascular Risk Factors in Patients with Type 2 Diabetes in Upper Egypt Villages
title_short	Assessment of Cardiovascular Risk Factors in Patients with Type 2 Diabetes in Upper Egypt Villages
title_full	Assessment of Cardiovascular Risk Factors in Patients with Type 2 Diabetes in Upper Egypt Villages
title_fullStr	Assessment of Cardiovascular Risk Factors in Patients with Type 2 Diabetes in Upper Egypt Villages
title_full_unstemmed	Assessment of Cardiovascular Risk Factors in Patients with Type 2 Diabetes in Upper Egypt Villages
title_sort	assessment of cardiovascular risk factors in patients with type 2 diabetes in upper egypt villages
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/abe5e36981cb45be8b0fdeaceda3c5d9
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Assessment of Cardiovascular Risk Factors in Patients with Type 2 Diabetes in Upper Egypt Villages

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