SIRT7-dependent deacetylation of the U3-55k protein controls pre-rRNA processing

SIRT7 is a protein deacetylase with important roles in rRNA synthesis, ribosome biogenesis and cell proliferation. Here the authors show a role of SIRT7 in rRNA maturation via deacetylation of U3-55k, a core component of the U3 snoRNP complex.

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Autores principales: Sifan Chen, Maximilian Felix Blank, Aishwarya Iyer, Bingding Huang, Lin Wang, Ingrid Grummt, Renate Voit
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/abe8d6944d854bd2b55474b4c6418e77
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spelling oai:doaj.org-article:abe8d6944d854bd2b55474b4c6418e772021-12-02T17:31:17ZSIRT7-dependent deacetylation of the U3-55k protein controls pre-rRNA processing10.1038/ncomms107342041-1723https://doaj.org/article/abe8d6944d854bd2b55474b4c6418e772016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10734https://doaj.org/toc/2041-1723SIRT7 is a protein deacetylase with important roles in rRNA synthesis, ribosome biogenesis and cell proliferation. Here the authors show a role of SIRT7 in rRNA maturation via deacetylation of U3-55k, a core component of the U3 snoRNP complex.Sifan ChenMaximilian Felix BlankAishwarya IyerBingding HuangLin WangIngrid GrummtRenate VoitNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sifan Chen
Maximilian Felix Blank
Aishwarya Iyer
Bingding Huang
Lin Wang
Ingrid Grummt
Renate Voit
SIRT7-dependent deacetylation of the U3-55k protein controls pre-rRNA processing
description SIRT7 is a protein deacetylase with important roles in rRNA synthesis, ribosome biogenesis and cell proliferation. Here the authors show a role of SIRT7 in rRNA maturation via deacetylation of U3-55k, a core component of the U3 snoRNP complex.
format article
author Sifan Chen
Maximilian Felix Blank
Aishwarya Iyer
Bingding Huang
Lin Wang
Ingrid Grummt
Renate Voit
author_facet Sifan Chen
Maximilian Felix Blank
Aishwarya Iyer
Bingding Huang
Lin Wang
Ingrid Grummt
Renate Voit
author_sort Sifan Chen
title SIRT7-dependent deacetylation of the U3-55k protein controls pre-rRNA processing
title_short SIRT7-dependent deacetylation of the U3-55k protein controls pre-rRNA processing
title_full SIRT7-dependent deacetylation of the U3-55k protein controls pre-rRNA processing
title_fullStr SIRT7-dependent deacetylation of the U3-55k protein controls pre-rRNA processing
title_full_unstemmed SIRT7-dependent deacetylation of the U3-55k protein controls pre-rRNA processing
title_sort sirt7-dependent deacetylation of the u3-55k protein controls pre-rrna processing
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/abe8d6944d854bd2b55474b4c6418e77
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AT bingdinghuang sirt7dependentdeacetylationoftheu355kproteincontrolsprerrnaprocessing
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