SIRT7-dependent deacetylation of the U3-55k protein controls pre-rRNA processing

SIRT7-dependent deacetylation of the U3-55k protein controls pre-rRNA processing

SIRT7 is a protein deacetylase with important roles in rRNA synthesis, ribosome biogenesis and cell proliferation. Here the authors show a role of SIRT7 in rRNA maturation via deacetylation of U3-55k, a core component of the U3 snoRNP complex.

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Autores principales: Sifan Chen, Maximilian Felix Blank, Aishwarya Iyer, Bingding Huang, Lin Wang, Ingrid Grummt, Renate Voit
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Science
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Acceso en línea:https://doaj.org/article/abe8d6944d854bd2b55474b4c6418e77
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