A cdk1 gradient guides surface contraction waves in oocytes

Surface contraction waves (SCWs) are prominent shape changes coupled to cell cycle transitions in oocytes. Here the authors show that SCWs are patterned by the spatiotemporal integration of two conserved modules, cdk1-cyclinB for cell cycle regulation and RhoA/Rok/NMYII for actomyosin contractility.

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Autores principales:	Johanna Bischof, Christoph A. Brand, Kálmán Somogyi, Imre Májer, Sarah Thome, Masashi Mori, Ulrich S. Schwarz, Péter Lénárt
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/abec266d937c4acfa74253dfd390e3c9
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spelling	oai:doaj.org-article:abec266d937c4acfa74253dfd390e3c92021-12-02T14:40:34ZA cdk1 gradient guides surface contraction waves in oocytes10.1038/s41467-017-00979-62041-1723https://doaj.org/article/abec266d937c4acfa74253dfd390e3c92017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00979-6https://doaj.org/toc/2041-1723Surface contraction waves (SCWs) are prominent shape changes coupled to cell cycle transitions in oocytes. Here the authors show that SCWs are patterned by the spatiotemporal integration of two conserved modules, cdk1-cyclinB for cell cycle regulation and RhoA/Rok/NMYII for actomyosin contractility.Johanna BischofChristoph A. BrandKálmán SomogyiImre MájerSarah ThomeMasashi MoriUlrich S. SchwarzPéter LénártNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Johanna Bischof Christoph A. Brand Kálmán Somogyi Imre Májer Sarah Thome Masashi Mori Ulrich S. Schwarz Péter Lénárt A cdk1 gradient guides surface contraction waves in oocytes
description	Surface contraction waves (SCWs) are prominent shape changes coupled to cell cycle transitions in oocytes. Here the authors show that SCWs are patterned by the spatiotemporal integration of two conserved modules, cdk1-cyclinB for cell cycle regulation and RhoA/Rok/NMYII for actomyosin contractility.
format	article
author	Johanna Bischof Christoph A. Brand Kálmán Somogyi Imre Májer Sarah Thome Masashi Mori Ulrich S. Schwarz Péter Lénárt
author_facet	Johanna Bischof Christoph A. Brand Kálmán Somogyi Imre Májer Sarah Thome Masashi Mori Ulrich S. Schwarz Péter Lénárt
author_sort	Johanna Bischof
title	A cdk1 gradient guides surface contraction waves in oocytes
title_short	A cdk1 gradient guides surface contraction waves in oocytes
title_full	A cdk1 gradient guides surface contraction waves in oocytes
title_fullStr	A cdk1 gradient guides surface contraction waves in oocytes
title_full_unstemmed	A cdk1 gradient guides surface contraction waves in oocytes
title_sort	cdk1 gradient guides surface contraction waves in oocytes
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/abec266d937c4acfa74253dfd390e3c9
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A cdk1 gradient guides surface contraction waves in oocytes

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