A cdk1 gradient guides surface contraction waves in oocytes

A cdk1 gradient guides surface contraction waves in oocytes

Surface contraction waves (SCWs) are prominent shape changes coupled to cell cycle transitions in oocytes. Here the authors show that SCWs are patterned by the spatiotemporal integration of two conserved modules, cdk1-cyclinB for cell cycle regulation and RhoA/Rok/NMYII for actomyosin contractility.

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Autores principales: Johanna Bischof, Christoph A. Brand, Kálmán Somogyi, Imre Májer, Sarah Thome, Masashi Mori, Ulrich S. Schwarz, Péter Lénárt
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Science
Q
Acceso en línea:https://doaj.org/article/abec266d937c4acfa74253dfd390e3c9
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