Controlled gene and drug release from a liposomal delivery platform triggered by X-ray radiation

X-ray radiation has excellent tissue penetration depth, making it a useful trigger for deep tissue cancer therapy. Here, the authors design X-ray triggered drug/gene-loaded liposomes by embedding photosensitizers and gold nanoparticles in the liposome bilayer, and demonstrate their efficacy in cance...

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Autores principales:	Wei Deng, Wenjie Chen, Sandhya Clement, Anna Guller, Zhenjun Zhao, Alexander Engel, Ewa M. Goldys
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/abf0504778b3459db5b34ae64fe4c946
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spelling	oai:doaj.org-article:abf0504778b3459db5b34ae64fe4c9462021-12-02T15:34:25ZControlled gene and drug release from a liposomal delivery platform triggered by X-ray radiation10.1038/s41467-018-05118-32041-1723https://doaj.org/article/abf0504778b3459db5b34ae64fe4c9462018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05118-3https://doaj.org/toc/2041-1723X-ray radiation has excellent tissue penetration depth, making it a useful trigger for deep tissue cancer therapy. Here, the authors design X-ray triggered drug/gene-loaded liposomes by embedding photosensitizers and gold nanoparticles in the liposome bilayer, and demonstrate their efficacy in cancer and gene therapy.Wei DengWenjie ChenSandhya ClementAnna GullerZhenjun ZhaoAlexander EngelEwa M. GoldysNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Wei Deng Wenjie Chen Sandhya Clement Anna Guller Zhenjun Zhao Alexander Engel Ewa M. Goldys Controlled gene and drug release from a liposomal delivery platform triggered by X-ray radiation
description	X-ray radiation has excellent tissue penetration depth, making it a useful trigger for deep tissue cancer therapy. Here, the authors design X-ray triggered drug/gene-loaded liposomes by embedding photosensitizers and gold nanoparticles in the liposome bilayer, and demonstrate their efficacy in cancer and gene therapy.
format	article
author	Wei Deng Wenjie Chen Sandhya Clement Anna Guller Zhenjun Zhao Alexander Engel Ewa M. Goldys
author_facet	Wei Deng Wenjie Chen Sandhya Clement Anna Guller Zhenjun Zhao Alexander Engel Ewa M. Goldys
author_sort	Wei Deng
title	Controlled gene and drug release from a liposomal delivery platform triggered by X-ray radiation
title_short	Controlled gene and drug release from a liposomal delivery platform triggered by X-ray radiation
title_full	Controlled gene and drug release from a liposomal delivery platform triggered by X-ray radiation
title_fullStr	Controlled gene and drug release from a liposomal delivery platform triggered by X-ray radiation
title_full_unstemmed	Controlled gene and drug release from a liposomal delivery platform triggered by X-ray radiation
title_sort	controlled gene and drug release from a liposomal delivery platform triggered by x-ray radiation
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/abf0504778b3459db5b34ae64fe4c946
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Controlled gene and drug release from a liposomal delivery platform triggered by X-ray radiation

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