Development of a potent embryonic chick lens model for studying congenital cataracts in vivo

Li et al. report an embryonic chick lens model to study the onset of congenital cataracts. By injecting recombinant retrovirus containing mutants that cause congenital cataract in lumen of embryonic chick lens, they show that their model exhibits cataract lens closely mimicking characteristics of hu...

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Autores principales: Zhen Li, Sumin Gu, Yumeng Quan, Kulandaiappan Varadaraj, Jean X. Jiang
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/abf0e834f148418fb4464418e4cc5a20
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spelling oai:doaj.org-article:abf0e834f148418fb4464418e4cc5a202021-12-02T15:52:46ZDevelopment of a potent embryonic chick lens model for studying congenital cataracts in vivo10.1038/s42003-021-01849-02399-3642https://doaj.org/article/abf0e834f148418fb4464418e4cc5a202021-03-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01849-0https://doaj.org/toc/2399-3642Li et al. report an embryonic chick lens model to study the onset of congenital cataracts. By injecting recombinant retrovirus containing mutants that cause congenital cataract in lumen of embryonic chick lens, they show that their model exhibits cataract lens closely mimicking characteristics of human congenital cataracts.Zhen LiSumin GuYumeng QuanKulandaiappan VaradarajJean X. JiangNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Zhen Li
Sumin Gu
Yumeng Quan
Kulandaiappan Varadaraj
Jean X. Jiang
Development of a potent embryonic chick lens model for studying congenital cataracts in vivo
description Li et al. report an embryonic chick lens model to study the onset of congenital cataracts. By injecting recombinant retrovirus containing mutants that cause congenital cataract in lumen of embryonic chick lens, they show that their model exhibits cataract lens closely mimicking characteristics of human congenital cataracts.
format article
author Zhen Li
Sumin Gu
Yumeng Quan
Kulandaiappan Varadaraj
Jean X. Jiang
author_facet Zhen Li
Sumin Gu
Yumeng Quan
Kulandaiappan Varadaraj
Jean X. Jiang
author_sort Zhen Li
title Development of a potent embryonic chick lens model for studying congenital cataracts in vivo
title_short Development of a potent embryonic chick lens model for studying congenital cataracts in vivo
title_full Development of a potent embryonic chick lens model for studying congenital cataracts in vivo
title_fullStr Development of a potent embryonic chick lens model for studying congenital cataracts in vivo
title_full_unstemmed Development of a potent embryonic chick lens model for studying congenital cataracts in vivo
title_sort development of a potent embryonic chick lens model for studying congenital cataracts in vivo
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/abf0e834f148418fb4464418e4cc5a20
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AT yumengquan developmentofapotentembryonicchicklensmodelforstudyingcongenitalcataractsinvivo
AT kulandaiappanvaradaraj developmentofapotentembryonicchicklensmodelforstudyingcongenitalcataractsinvivo
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