Activation of the GLP-1 receptor by chloropyrimidine derivatives

The anti-diabetic activities of a series of chloropyrimidine derviatives 2a-k and 4a-k were investigated after they were designed, synthesized, and docked against the GLP-1 receptor target. In comparison to exenatide, which was utilized as a reference drug, the three chloropyrimidine synthesized com...

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Autores principales: Shaikha S. AlNeyadi, Abdu Adem, Naheed Amer, Mohammad A Ghattas, Noor Atatreh, Alaa A. Salem, Ibrahim M. Abdou
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/abf9bb2a2d3841919333302b3a95cdb0
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