Ureter regeneration-the proper scaffold has to be defined.

The aim of this study was to compare two different acellular scaffolds: natural and synthetic, for urinary conduit construction and ureter segment reconstruction. Acellular aortic arch (AAM) and poly(L-lactide-co-caprolactone) (PLCL) were used in 24 rats for ureter reconstruction in both tested grou...

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Autores principales:	Tomasz Kloskowski, Arkadiusz Jundziłł, Tomasz Kowalczyk, Maciej Nowacki, Magdalena Bodnar, Andrzej Marszałek, Marta Pokrywczyńska, Małgorzata Frontczak-Baniewicz, Tomasz A Kowalewski, Piotr Chłosta, Tomasz Drewa
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2014
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/abffc6e5e8e9435f8cdb7e8518fb4562
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spelling	oai:doaj.org-article:abffc6e5e8e9435f8cdb7e8518fb45622021-11-25T06:03:02ZUreter regeneration-the proper scaffold has to be defined.1932-620310.1371/journal.pone.0106023https://doaj.org/article/abffc6e5e8e9435f8cdb7e8518fb45622014-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25162415/?tool=EBIhttps://doaj.org/toc/1932-6203The aim of this study was to compare two different acellular scaffolds: natural and synthetic, for urinary conduit construction and ureter segment reconstruction. Acellular aortic arch (AAM) and poly(L-lactide-co-caprolactone) (PLCL) were used in 24 rats for ureter reconstruction in both tested groups. Follow-up period was 4 weeks. Intravenous pyelography, histological and immunohistochemical analysis were performed. All animals survived surgical procedures. Patent uretero-conduit junction was observed only in one case using PLCL. In case of ureter segment reconstruction ureters were patent in one case using AAM and in four cases using PLCL scaffolds. Regeneration of urothelium layer and focal regeneration of smooth muscle layer was observed on both tested scaffolds. Obtained results indicates that synthetic acellular PLCL scaffolds showed better properties for ureter reconstruction than naturally derived acellular aortic arch.Tomasz KloskowskiArkadiusz JundziłłTomasz KowalczykMaciej NowackiMagdalena BodnarAndrzej MarszałekMarta PokrywczyńskaMałgorzata Frontczak-BaniewiczTomasz A KowalewskiPiotr ChłostaTomasz DrewaPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 8, p e106023 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Tomasz Kloskowski Arkadiusz Jundziłł Tomasz Kowalczyk Maciej Nowacki Magdalena Bodnar Andrzej Marszałek Marta Pokrywczyńska Małgorzata Frontczak-Baniewicz Tomasz A Kowalewski Piotr Chłosta Tomasz Drewa Ureter regeneration-the proper scaffold has to be defined.
description	The aim of this study was to compare two different acellular scaffolds: natural and synthetic, for urinary conduit construction and ureter segment reconstruction. Acellular aortic arch (AAM) and poly(L-lactide-co-caprolactone) (PLCL) were used in 24 rats for ureter reconstruction in both tested groups. Follow-up period was 4 weeks. Intravenous pyelography, histological and immunohistochemical analysis were performed. All animals survived surgical procedures. Patent uretero-conduit junction was observed only in one case using PLCL. In case of ureter segment reconstruction ureters were patent in one case using AAM and in four cases using PLCL scaffolds. Regeneration of urothelium layer and focal regeneration of smooth muscle layer was observed on both tested scaffolds. Obtained results indicates that synthetic acellular PLCL scaffolds showed better properties for ureter reconstruction than naturally derived acellular aortic arch.
format	article
author	Tomasz Kloskowski Arkadiusz Jundziłł Tomasz Kowalczyk Maciej Nowacki Magdalena Bodnar Andrzej Marszałek Marta Pokrywczyńska Małgorzata Frontczak-Baniewicz Tomasz A Kowalewski Piotr Chłosta Tomasz Drewa
author_facet	Tomasz Kloskowski Arkadiusz Jundziłł Tomasz Kowalczyk Maciej Nowacki Magdalena Bodnar Andrzej Marszałek Marta Pokrywczyńska Małgorzata Frontczak-Baniewicz Tomasz A Kowalewski Piotr Chłosta Tomasz Drewa
author_sort	Tomasz Kloskowski
title	Ureter regeneration-the proper scaffold has to be defined.
title_short	Ureter regeneration-the proper scaffold has to be defined.
title_full	Ureter regeneration-the proper scaffold has to be defined.
title_fullStr	Ureter regeneration-the proper scaffold has to be defined.
title_full_unstemmed	Ureter regeneration-the proper scaffold has to be defined.
title_sort	ureter regeneration-the proper scaffold has to be defined.
publisher	Public Library of Science (PLoS)
publishDate	2014
url	https://doaj.org/article/abffc6e5e8e9435f8cdb7e8518fb4562
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Ureter regeneration-the proper scaffold has to be defined.

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