Bacterial superantigens promote acute nasopharyngeal infection by Streptococcus pyogenes in a human MHC Class II-dependent manner.

Bacterial superantigens promote acute nasopharyngeal infection by Streptococcus pyogenes in a human MHC Class II-dependent manner.

Establishing the genetic determinants of niche adaptation by microbial pathogens to specific hosts is important for the management and control of infectious disease. Streptococcus pyogenes is a globally prominent human-specific bacterial pathogen that secretes superantigens (SAgs) as 'trademark...

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Detalles Bibliográficos
Autores principales: Katherine J Kasper, Joseph J Zeppa, Adrienne T Wakabayashi, Stacey X Xu, Delfina M Mazzuca, Ian Welch, Miren L Baroja, Malak Kotb, Ewa Cairns, P Patrick Cleary, S M Mansour Haeryfar, John K McCormick
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Immunologic diseases. Allergy
RC581-607
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/ac1b66d7d94a4ec6aeab4da369e8e0a4
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