The benefit of atrial septal defect closure in elderly patients*

Monika Komar, Tadeusz Przewlocki, Maria Olszowska, Bartosz Sobien, Piotr Podolec Department of Cardiac and Vascular Diseases, Institute of Cardiology, Jagiellonian University, Krakow, Poland Objective: Closure of an atrial septal defect in elderly patients is controversial. The aim of the study wa...

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Autores principales:	Komar M, Przewlocki T, Olszowska M, Sobien B, Podolec P
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	atrial septal defect transcatheter closure elderly cardiopulmonary exercise test quality of life Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/ac1bb86e3e21465fb5db7053fdf8016f
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spelling	oai:doaj.org-article:ac1bb86e3e21465fb5db7053fdf8016f2021-12-02T00:33:23ZThe benefit of atrial septal defect closure in elderly patients*1178-1998https://doaj.org/article/ac1bb86e3e21465fb5db7053fdf8016f2014-07-01T00:00:00Zhttps://www.dovepress.com/the-benefit-of-atrial-septal-defect-closure-in-elderly-patients-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Monika Komar, Tadeusz Przewlocki, Maria Olszowska, Bartosz Sobien, Piotr Podolec Department of Cardiac and Vascular Diseases, Institute of Cardiology, Jagiellonian University, Krakow, Poland Objective: Closure of an atrial septal defect in elderly patients is controversial. The aim of the study was to evaluate the outcomes of transcatheter closure of secundum atrial septal defects (ASDs) in elderly patients.Patients and methods: From a total of 488 patients with ASDs who underwent transcatheter closure, 75 patients aged over 60 years (45 female, 30 male) with a mean age of 65.3±15.7 (60–75) years were analyzed. All patients had an isolated secundum ASD with a mean pulmonary blood flow:systemic blood flow of 2.84±1.9 (1.5–3.9). Symptom-limited treadmill exercise tests with respiratory gas-exchange analysis and transthoracic color Doppler echocardiographic study, as well as quality of life measured using the Short Form (36) Health Survey (SF-36) were repeated in all patients before the procedure and after 12 months of follow-up.Results: The atrial septal device was successfully implanted in all patients (procedure time 37.7±4.5 [13–59] minutes, fluoroscopy time 11.2±9.9 [6–40] minutes). There were no major complications. The defect echo diameter was 17.7±15.8 (12–30) mm. The mean balloon-stretched diameter of ASDs was 22.4±7.9 (14–34) mm. The diameter of the implanted devices ranged from 16 to 34 mm. Significant improvement of exercise capacity was noted at 6 and 12 months after the procedure. Exercise time within 6 months of ASD closure was longer (P<0.001) compared to baseline values, and also oxygen consumption increased (P<0.001). Seven quality-of-life parameters (except mental health) improved at 12-month follow-up compared to baseline data. The mean SF-36 scale increased significantly in 66 (88%) patients, with a mean of 46.2±19.1 (5–69). As early as 1 month after the procedure, a significant decrease of the right ventricular dimension and the right atrium dimension was observed (P<0.001). The right ventricular dimension decreased in 67 patients (89.3%).Conclusion: Closure of ASDs in elderly patients caused significant clinical and hemodynamic improvement after percutaneous treatment, which was maintained during long-term follow-up, justifying this procedure in old age. Keywords: atrial septal defect, transcatheter closure, elderly, cardiopulmonary exercise test, quality of lifeKomar MPrzewlocki TOlszowska MSobien BPodolec PDove Medical Pressarticleatrial septal defecttranscatheter closureelderlycardiopulmonary exercise testquality of lifeGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 9, Pp 1101-1107 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	atrial septal defect transcatheter closure elderly cardiopulmonary exercise test quality of life Geriatrics RC952-954.6
spellingShingle	atrial septal defect transcatheter closure elderly cardiopulmonary exercise test quality of life Geriatrics RC952-954.6 Komar M Przewlocki T Olszowska M Sobien B Podolec P The benefit of atrial septal defect closure in elderly patients*
description	Monika Komar, Tadeusz Przewlocki, Maria Olszowska, Bartosz Sobien, Piotr Podolec Department of Cardiac and Vascular Diseases, Institute of Cardiology, Jagiellonian University, Krakow, Poland Objective: Closure of an atrial septal defect in elderly patients is controversial. The aim of the study was to evaluate the outcomes of transcatheter closure of secundum atrial septal defects (ASDs) in elderly patients.Patients and methods: From a total of 488 patients with ASDs who underwent transcatheter closure, 75 patients aged over 60 years (45 female, 30 male) with a mean age of 65.3±15.7 (60–75) years were analyzed. All patients had an isolated secundum ASD with a mean pulmonary blood flow:systemic blood flow of 2.84±1.9 (1.5–3.9). Symptom-limited treadmill exercise tests with respiratory gas-exchange analysis and transthoracic color Doppler echocardiographic study, as well as quality of life measured using the Short Form (36) Health Survey (SF-36) were repeated in all patients before the procedure and after 12 months of follow-up.Results: The atrial septal device was successfully implanted in all patients (procedure time 37.7±4.5 [13–59] minutes, fluoroscopy time 11.2±9.9 [6–40] minutes). There were no major complications. The defect echo diameter was 17.7±15.8 (12–30) mm. The mean balloon-stretched diameter of ASDs was 22.4±7.9 (14–34) mm. The diameter of the implanted devices ranged from 16 to 34 mm. Significant improvement of exercise capacity was noted at 6 and 12 months after the procedure. Exercise time within 6 months of ASD closure was longer (P<0.001) compared to baseline values, and also oxygen consumption increased (P<0.001). Seven quality-of-life parameters (except mental health) improved at 12-month follow-up compared to baseline data. The mean SF-36 scale increased significantly in 66 (88%) patients, with a mean of 46.2±19.1 (5–69). As early as 1 month after the procedure, a significant decrease of the right ventricular dimension and the right atrium dimension was observed (P<0.001). The right ventricular dimension decreased in 67 patients (89.3%).Conclusion: Closure of ASDs in elderly patients caused significant clinical and hemodynamic improvement after percutaneous treatment, which was maintained during long-term follow-up, justifying this procedure in old age. Keywords: atrial septal defect, transcatheter closure, elderly, cardiopulmonary exercise test, quality of life
format	article
author	Komar M Przewlocki T Olszowska M Sobien B Podolec P
author_facet	Komar M Przewlocki T Olszowska M Sobien B Podolec P
author_sort	Komar M
title	The benefit of atrial septal defect closure in elderly patients*
title_short	The benefit of atrial septal defect closure in elderly patients*
title_full	The benefit of atrial septal defect closure in elderly patients*
title_fullStr	The benefit of atrial septal defect closure in elderly patients*
title_full_unstemmed	The benefit of atrial septal defect closure in elderly patients*
title_sort	benefit of atrial septal defect closure in elderly patients*
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/ac1bb86e3e21465fb5db7053fdf8016f
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The benefit of atrial septal defect closure in elderly patients*

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