Molecular basis of EphA2 recognition by gHgL from gammaherpesviruses

Molecular basis of EphA2 recognition by gHgL from gammaherpesviruses

EphA2 is the specific entry receptor for both human γ-herpesviruses Kaposi sarcoma associated herpesvirus (KSHV) and Epstein-Barr virus (EBV). Here, the authors present the crystal structures of the EphA2 ligand binding domain (LBD) bound to the viral glycoprotein gHgL from EBV and KSHV and further...

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Autores principales: Chao Su, Lili Wu, Yan Chai, Jianxun Qi, Shuguang Tan, George F. Gao, Hao Song, Jinghua Yan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/ac26222e07064a76b8a070ea9eb86d83
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