The Impact of Early-Life Exposure to Air-borne Environmental Insults on the Function of the Airway Epithelium in Asthma

The airway <a title="Learn more about Epithelium" href="https://www.sciencedirect.com/topics/medicine-and-dentistry/epithelium">epithelium</a> is both a physical barrier protecting the airways from environmental insults and a significant component of the <a title=&...

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Autores principales:	Kirsten Spann, Natale Snape, Engin Baturcam, Emmanuelle Fantino
Formato:	article
Lenguaje:	EN
Publicado:	Ubiquity Press 2016
Materias:	asthma allergens air pollution virus epithelium early life airway remodeling immunity Infectious and parasitic diseases RC109-216 Public aspects of medicine RA1-1270
Acceso en línea:	https://doaj.org/article/ac2a80f3996b4695ae21d8f818954f3e
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id	oai:doaj.org-article:ac2a80f3996b4695ae21d8f818954f3e
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spelling	oai:doaj.org-article:ac2a80f3996b4695ae21d8f818954f3e2021-12-02T07:41:18ZThe Impact of Early-Life Exposure to Air-borne Environmental Insults on the Function of the Airway Epithelium in Asthma2214-999610.1016/j.aogh.2016.01.007https://doaj.org/article/ac2a80f3996b4695ae21d8f818954f3e2016-06-01T00:00:00Zhttps://annalsofglobalhealth.org/articles/1147https://doaj.org/toc/2214-9996The airway <a title="Learn more about Epithelium" href="https://www.sciencedirect.com/topics/medicine-and-dentistry/epithelium">epithelium</a> is both a physical barrier protecting the airways from environmental insults and a significant component of the <a title="Learn more about Innate Immune Response" href="https://www.sciencedirect.com/topics/medicine-and-dentistry/innate-immune-response">innate immune response</a>. There is growing evidence that exposure of the airway epithelium to environmental insults in early life may lead to permanent changes in structure and function that underlie the development of asthma. Here we review the current published evidence concerning the link between asthma and epithelial damage within the airways and identify gaps in knowledge for future studies.Kirsten SpannNatale SnapeEngin BaturcamEmmanuelle FantinoUbiquity Pressarticleasthmaallergensair pollutionvirusepitheliumearly lifeairway remodelingimmunityInfectious and parasitic diseasesRC109-216Public aspects of medicineRA1-1270ENAnnals of Global Health, Vol 82, Iss 1, Pp 28-40 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	asthma allergens air pollution virus epithelium early life airway remodeling immunity Infectious and parasitic diseases RC109-216 Public aspects of medicine RA1-1270
spellingShingle	asthma allergens air pollution virus epithelium early life airway remodeling immunity Infectious and parasitic diseases RC109-216 Public aspects of medicine RA1-1270 Kirsten Spann Natale Snape Engin Baturcam Emmanuelle Fantino The Impact of Early-Life Exposure to Air-borne Environmental Insults on the Function of the Airway Epithelium in Asthma
description	The airway <a title="Learn more about Epithelium" href="https://www.sciencedirect.com/topics/medicine-and-dentistry/epithelium">epithelium</a> is both a physical barrier protecting the airways from environmental insults and a significant component of the <a title="Learn more about Innate Immune Response" href="https://www.sciencedirect.com/topics/medicine-and-dentistry/innate-immune-response">innate immune response</a>. There is growing evidence that exposure of the airway epithelium to environmental insults in early life may lead to permanent changes in structure and function that underlie the development of asthma. Here we review the current published evidence concerning the link between asthma and epithelial damage within the airways and identify gaps in knowledge for future studies.
format	article
author	Kirsten Spann Natale Snape Engin Baturcam Emmanuelle Fantino
author_facet	Kirsten Spann Natale Snape Engin Baturcam Emmanuelle Fantino
author_sort	Kirsten Spann
title	The Impact of Early-Life Exposure to Air-borne Environmental Insults on the Function of the Airway Epithelium in Asthma
title_short	The Impact of Early-Life Exposure to Air-borne Environmental Insults on the Function of the Airway Epithelium in Asthma
title_full	The Impact of Early-Life Exposure to Air-borne Environmental Insults on the Function of the Airway Epithelium in Asthma
title_fullStr	The Impact of Early-Life Exposure to Air-borne Environmental Insults on the Function of the Airway Epithelium in Asthma
title_full_unstemmed	The Impact of Early-Life Exposure to Air-borne Environmental Insults on the Function of the Airway Epithelium in Asthma
title_sort	impact of early-life exposure to air-borne environmental insults on the function of the airway epithelium in asthma
publisher	Ubiquity Press
publishDate	2016
url	https://doaj.org/article/ac2a80f3996b4695ae21d8f818954f3e
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The Impact of Early-Life Exposure to Air-borne Environmental Insults on the Function of the Airway Epithelium in Asthma

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