Expanding the genetic code of Mus musculus
Expanding the genetic code with unnatural amino acids in model organisms is a powerful tool for investigatingin vivocellular proteins and processes. Here the authors re-engineer the amber stop codon in laboratory mice to allow site-specific incorporation of unnatural amino acids in target proteins.
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Nature Portfolio
2017
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oai:doaj.org-article:ac2bc2b9bb0a4eff862cfae10aed8d372021-12-02T15:38:39ZExpanding the genetic code of Mus musculus10.1038/ncomms145682041-1723https://doaj.org/article/ac2bc2b9bb0a4eff862cfae10aed8d372017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14568https://doaj.org/toc/2041-1723Expanding the genetic code with unnatural amino acids in model organisms is a powerful tool for investigatingin vivocellular proteins and processes. Here the authors re-engineer the amber stop codon in laboratory mice to allow site-specific incorporation of unnatural amino acids in target proteins.Songmi HanAerin YangSoonjang LeeHan-Woong LeeChan Bae ParkHee-Sung ParkNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-7 (2017) |
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Science Q |
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Science Q Songmi Han Aerin Yang Soonjang Lee Han-Woong Lee Chan Bae Park Hee-Sung Park Expanding the genetic code of Mus musculus |
description |
Expanding the genetic code with unnatural amino acids in model organisms is a powerful tool for investigatingin vivocellular proteins and processes. Here the authors re-engineer the amber stop codon in laboratory mice to allow site-specific incorporation of unnatural amino acids in target proteins. |
format |
article |
author |
Songmi Han Aerin Yang Soonjang Lee Han-Woong Lee Chan Bae Park Hee-Sung Park |
author_facet |
Songmi Han Aerin Yang Soonjang Lee Han-Woong Lee Chan Bae Park Hee-Sung Park |
author_sort |
Songmi Han |
title |
Expanding the genetic code of Mus musculus |
title_short |
Expanding the genetic code of Mus musculus |
title_full |
Expanding the genetic code of Mus musculus |
title_fullStr |
Expanding the genetic code of Mus musculus |
title_full_unstemmed |
Expanding the genetic code of Mus musculus |
title_sort |
expanding the genetic code of mus musculus |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/ac2bc2b9bb0a4eff862cfae10aed8d37 |
work_keys_str_mv |
AT songmihan expandingthegeneticcodeofmusmusculus AT aerinyang expandingthegeneticcodeofmusmusculus AT soonjanglee expandingthegeneticcodeofmusmusculus AT hanwoonglee expandingthegeneticcodeofmusmusculus AT chanbaepark expandingthegeneticcodeofmusmusculus AT heesungpark expandingthegeneticcodeofmusmusculus |
_version_ |
1718386133751037952 |