Expanding the genetic code of Mus musculus

Expanding the genetic code with unnatural amino acids in model organisms is a powerful tool for investigatingin vivocellular proteins and processes. Here the authors re-engineer the amber stop codon in laboratory mice to allow site-specific incorporation of unnatural amino acids in target proteins.

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Autores principales: Songmi Han, Aerin Yang, Soonjang Lee, Han-Woong Lee, Chan Bae Park, Hee-Sung Park
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/ac2bc2b9bb0a4eff862cfae10aed8d37
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spelling oai:doaj.org-article:ac2bc2b9bb0a4eff862cfae10aed8d372021-12-02T15:38:39ZExpanding the genetic code of Mus musculus10.1038/ncomms145682041-1723https://doaj.org/article/ac2bc2b9bb0a4eff862cfae10aed8d372017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14568https://doaj.org/toc/2041-1723Expanding the genetic code with unnatural amino acids in model organisms is a powerful tool for investigatingin vivocellular proteins and processes. Here the authors re-engineer the amber stop codon in laboratory mice to allow site-specific incorporation of unnatural amino acids in target proteins.Songmi HanAerin YangSoonjang LeeHan-Woong LeeChan Bae ParkHee-Sung ParkNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Songmi Han
Aerin Yang
Soonjang Lee
Han-Woong Lee
Chan Bae Park
Hee-Sung Park
Expanding the genetic code of Mus musculus
description Expanding the genetic code with unnatural amino acids in model organisms is a powerful tool for investigatingin vivocellular proteins and processes. Here the authors re-engineer the amber stop codon in laboratory mice to allow site-specific incorporation of unnatural amino acids in target proteins.
format article
author Songmi Han
Aerin Yang
Soonjang Lee
Han-Woong Lee
Chan Bae Park
Hee-Sung Park
author_facet Songmi Han
Aerin Yang
Soonjang Lee
Han-Woong Lee
Chan Bae Park
Hee-Sung Park
author_sort Songmi Han
title Expanding the genetic code of Mus musculus
title_short Expanding the genetic code of Mus musculus
title_full Expanding the genetic code of Mus musculus
title_fullStr Expanding the genetic code of Mus musculus
title_full_unstemmed Expanding the genetic code of Mus musculus
title_sort expanding the genetic code of mus musculus
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/ac2bc2b9bb0a4eff862cfae10aed8d37
work_keys_str_mv AT songmihan expandingthegeneticcodeofmusmusculus
AT aerinyang expandingthegeneticcodeofmusmusculus
AT soonjanglee expandingthegeneticcodeofmusmusculus
AT hanwoonglee expandingthegeneticcodeofmusmusculus
AT chanbaepark expandingthegeneticcodeofmusmusculus
AT heesungpark expandingthegeneticcodeofmusmusculus
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