The pharmacological management of erectile dysfunction – Update 2016

Erectile dysfunction (ED) is a trivial condition with a prevailing incidence worldwide. Phosphodiesterase-5 inhibitors (PDE-5) have revolutionised the treatment of ED and are regarded as one of the most successful drug groups in modern medicine. Generally PDE-5 inhibitors are well tolerated and the...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autor principal: André Marais
Formato: article
Lenguaje:EN
Publicado: AOSIS 2016
Materias:
R
Acceso en línea:https://doaj.org/article/ac2c0879c48f4050a954caea45b7c80c
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:ac2c0879c48f4050a954caea45b7c80c
record_format dspace
spelling oai:doaj.org-article:ac2c0879c48f4050a954caea45b7c80c2021-11-24T07:44:18ZThe pharmacological management of erectile dysfunction – Update 20162078-61902078-620410.4102/safp.v58i4.4521https://doaj.org/article/ac2c0879c48f4050a954caea45b7c80c2016-08-01T00:00:00Zhttps://safpj.co.za/index.php/safpj/article/view/4521https://doaj.org/toc/2078-6190https://doaj.org/toc/2078-6204Erectile dysfunction (ED) is a trivial condition with a prevailing incidence worldwide. Phosphodiesterase-5 inhibitors (PDE-5) have revolutionised the treatment of ED and are regarded as one of the most successful drug groups in modern medicine. Generally PDE-5 inhibitors are well tolerated and the incidence of side-effects is low, however a small percentage of individuals experience headache, flushing and abdominal discomfort, resulting in discontinuation of therapy. This has led to the development of second generation PDE-5 inhibitors, displaying more selectivity for the PDE-5 enzyme thereby reducing treatment interruption and improving compliance. Several other treatment modalities, including testosterone replacement therapy and prostaglandin administration are available for resistant or failed first-line treatment. This review provides an update on the current, and future, available drugs used in the management of ED.André MaraisAOSISarticlecardiovascular diseaseerectile dysfunctionphosphodiesterase-5 inhibitorsprostaglandintestosteroneMedicineRENSouth African Family Practice, Vol 58, Iss 4, Pp 10-14 (2016)
institution DOAJ
collection DOAJ
language EN
topic cardiovascular disease
erectile dysfunction
phosphodiesterase-5 inhibitors
prostaglandin
testosterone
Medicine
R
spellingShingle cardiovascular disease
erectile dysfunction
phosphodiesterase-5 inhibitors
prostaglandin
testosterone
Medicine
R
André Marais
The pharmacological management of erectile dysfunction – Update 2016
description Erectile dysfunction (ED) is a trivial condition with a prevailing incidence worldwide. Phosphodiesterase-5 inhibitors (PDE-5) have revolutionised the treatment of ED and are regarded as one of the most successful drug groups in modern medicine. Generally PDE-5 inhibitors are well tolerated and the incidence of side-effects is low, however a small percentage of individuals experience headache, flushing and abdominal discomfort, resulting in discontinuation of therapy. This has led to the development of second generation PDE-5 inhibitors, displaying more selectivity for the PDE-5 enzyme thereby reducing treatment interruption and improving compliance. Several other treatment modalities, including testosterone replacement therapy and prostaglandin administration are available for resistant or failed first-line treatment. This review provides an update on the current, and future, available drugs used in the management of ED.
format article
author André Marais
author_facet André Marais
author_sort André Marais
title The pharmacological management of erectile dysfunction – Update 2016
title_short The pharmacological management of erectile dysfunction – Update 2016
title_full The pharmacological management of erectile dysfunction – Update 2016
title_fullStr The pharmacological management of erectile dysfunction – Update 2016
title_full_unstemmed The pharmacological management of erectile dysfunction – Update 2016
title_sort pharmacological management of erectile dysfunction – update 2016
publisher AOSIS
publishDate 2016
url https://doaj.org/article/ac2c0879c48f4050a954caea45b7c80c
work_keys_str_mv AT andremarais thepharmacologicalmanagementoferectiledysfunctionupdate2016
AT andremarais pharmacologicalmanagementoferectiledysfunctionupdate2016
_version_ 1718415877895880704