Amoeboid-mesenchymal migration plasticity promotes invasion only in complex heterogeneous microenvironments

Abstract During tissue invasion individual tumor cells exhibit two interconvertible migration modes, namely mesenchymal and amoeboid migration. The cellular microenvironment triggers the switch between both modes, thereby allowing adaptation to dynamic conditions. It is, however, unclear if this amo...

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Autores principales: Katrin Talkenberger, Elisabetta Ada Cavalcanti-Adam, Anja Voss-Böhme, Andreas Deutsch
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/ac30830f1fea4192b35fc976d9691ea0
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