An Oligomannuronic Acid-Sialic Acid Conjugate Capable of Inhibiting Aβ42 Aggregation and Alleviating the Inflammatory Response of BV-2 Microglia

Oligomannuronic acid (MOS) from seaweed has antioxidant and anti-inflammatory activities. In this study, MOS was activated at the terminal to obtain three different graft complexes modified with sialic acid moiety (MOS-Sia). The results show that MOS-Sia addition can reduce the β-structure formation...

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Bibliographic Details
Main Authors: Jianrong Wu, Miaosen Wu, Hongtao Zhang, Xiaobei Zhan, Nian Wu
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/ac38baa10c9249f0b30fe5bcf158bc48
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