Cloning and identification of PK15 cells for enhanced replication of classical swine fever virus

Classical swine fever virus (CSFV) causes an economically important and highly contagious disease of pigs, leading to economic losses around the world. Attenuated live vaccines with CSFV antigens have played an important role in the prevention and control of the disease. Porcine kidney 15 (PK15) cel...

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Autores principales: Yin Mei, Hu Dongfang, Li Peng, Kong Lingyun, Ning Hongmei, Yue Feng, Jiang Jinqing, Wang Xuannian
Formato: article
Lenguaje:EN
Publicado: Sciendo 2020
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Acceso en línea:https://doaj.org/article/ac4316986c96497d89dddc3238b5caba
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spelling oai:doaj.org-article:ac4316986c96497d89dddc3238b5caba2021-12-05T14:11:08ZCloning and identification of PK15 cells for enhanced replication of classical swine fever virus2450-860810.2478/jvetres-2020-0020https://doaj.org/article/ac4316986c96497d89dddc3238b5caba2020-03-01T00:00:00Zhttps://doi.org/10.2478/jvetres-2020-0020https://doaj.org/toc/2450-8608Classical swine fever virus (CSFV) causes an economically important and highly contagious disease of pigs, leading to economic losses around the world. Attenuated live vaccines with CSFV antigens have played an important role in the prevention and control of the disease. Porcine kidney 15 (PK15) cells have been widely used for the propagation of CSFV, but this cell line is not efficient or homogeneously susceptible to viral infection.Yin MeiHu DongfangLi PengKong LingyunNing HongmeiYue FengJiang JinqingWang XuannianSciendoarticleclassical swine fever viruspk15high-permissive cellscell cloningvaccine productionVeterinary medicineSF600-1100ENJournal of Veterinary Research, Vol 64, Iss 1, Pp 9-14 (2020)
institution DOAJ
collection DOAJ
language EN
topic classical swine fever virus
pk15
high-permissive cells
cell cloning
vaccine production
Veterinary medicine
SF600-1100
spellingShingle classical swine fever virus
pk15
high-permissive cells
cell cloning
vaccine production
Veterinary medicine
SF600-1100
Yin Mei
Hu Dongfang
Li Peng
Kong Lingyun
Ning Hongmei
Yue Feng
Jiang Jinqing
Wang Xuannian
Cloning and identification of PK15 cells for enhanced replication of classical swine fever virus
description Classical swine fever virus (CSFV) causes an economically important and highly contagious disease of pigs, leading to economic losses around the world. Attenuated live vaccines with CSFV antigens have played an important role in the prevention and control of the disease. Porcine kidney 15 (PK15) cells have been widely used for the propagation of CSFV, but this cell line is not efficient or homogeneously susceptible to viral infection.
format article
author Yin Mei
Hu Dongfang
Li Peng
Kong Lingyun
Ning Hongmei
Yue Feng
Jiang Jinqing
Wang Xuannian
author_facet Yin Mei
Hu Dongfang
Li Peng
Kong Lingyun
Ning Hongmei
Yue Feng
Jiang Jinqing
Wang Xuannian
author_sort Yin Mei
title Cloning and identification of PK15 cells for enhanced replication of classical swine fever virus
title_short Cloning and identification of PK15 cells for enhanced replication of classical swine fever virus
title_full Cloning and identification of PK15 cells for enhanced replication of classical swine fever virus
title_fullStr Cloning and identification of PK15 cells for enhanced replication of classical swine fever virus
title_full_unstemmed Cloning and identification of PK15 cells for enhanced replication of classical swine fever virus
title_sort cloning and identification of pk15 cells for enhanced replication of classical swine fever virus
publisher Sciendo
publishDate 2020
url https://doaj.org/article/ac4316986c96497d89dddc3238b5caba
work_keys_str_mv AT yinmei cloningandidentificationofpk15cellsforenhancedreplicationofclassicalswinefevervirus
AT hudongfang cloningandidentificationofpk15cellsforenhancedreplicationofclassicalswinefevervirus
AT lipeng cloningandidentificationofpk15cellsforenhancedreplicationofclassicalswinefevervirus
AT konglingyun cloningandidentificationofpk15cellsforenhancedreplicationofclassicalswinefevervirus
AT ninghongmei cloningandidentificationofpk15cellsforenhancedreplicationofclassicalswinefevervirus
AT yuefeng cloningandidentificationofpk15cellsforenhancedreplicationofclassicalswinefevervirus
AT jiangjinqing cloningandidentificationofpk15cellsforenhancedreplicationofclassicalswinefevervirus
AT wangxuannian cloningandidentificationofpk15cellsforenhancedreplicationofclassicalswinefevervirus
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