CASSPER is a semantic segmentation-based particle picking algorithm for single-particle cryo-electron microscopy

George, Assaiya et al. develop a deep learning tool, CASSPER, that automates the detection of protein particles in transmission microscope images. This algorithm uses semantic segmentation and visually prepared training samples to capture the differences in the transmission intensities of microscope...

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Autores principales: Blesson George, Anshul Assaiya, Robin J. Roy, Ajit Kembhavi, Radha Chauhan, Geetha Paul, Janesh Kumar, Ninan S. Philip
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/ac44a665905d4502a0e70a0390fc2cd0
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Sumario:George, Assaiya et al. develop a deep learning tool, CASSPER, that automates the detection of protein particles in transmission microscope images. This algorithm uses semantic segmentation and visually prepared training samples to capture the differences in the transmission intensities of microscope images, enabling automation of data processing.