CASSPER is a semantic segmentation-based particle picking algorithm for single-particle cryo-electron microscopy

George, Assaiya et al. develop a deep learning tool, CASSPER, that automates the detection of protein particles in transmission microscope images. This algorithm uses semantic segmentation and visually prepared training samples to capture the differences in the transmission intensities of microscope...

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Autores principales:	Blesson George, Anshul Assaiya, Robin J. Roy, Ajit Kembhavi, Radha Chauhan, Geetha Paul, Janesh Kumar, Ninan S. Philip
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/ac44a665905d4502a0e70a0390fc2cd0
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id	oai:doaj.org-article:ac44a665905d4502a0e70a0390fc2cd0
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spelling	oai:doaj.org-article:ac44a665905d4502a0e70a0390fc2cd02021-12-02T14:03:56ZCASSPER is a semantic segmentation-based particle picking algorithm for single-particle cryo-electron microscopy10.1038/s42003-021-01721-12399-3642https://doaj.org/article/ac44a665905d4502a0e70a0390fc2cd02021-02-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01721-1https://doaj.org/toc/2399-3642George, Assaiya et al. develop a deep learning tool, CASSPER, that automates the detection of protein particles in transmission microscope images. This algorithm uses semantic segmentation and visually prepared training samples to capture the differences in the transmission intensities of microscope images, enabling automation of data processing.Blesson GeorgeAnshul AssaiyaRobin J. RoyAjit KembhaviRadha ChauhanGeetha PaulJanesh KumarNinan S. PhilipNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Blesson George Anshul Assaiya Robin J. Roy Ajit Kembhavi Radha Chauhan Geetha Paul Janesh Kumar Ninan S. Philip CASSPER is a semantic segmentation-based particle picking algorithm for single-particle cryo-electron microscopy
description	George, Assaiya et al. develop a deep learning tool, CASSPER, that automates the detection of protein particles in transmission microscope images. This algorithm uses semantic segmentation and visually prepared training samples to capture the differences in the transmission intensities of microscope images, enabling automation of data processing.
format	article
author	Blesson George Anshul Assaiya Robin J. Roy Ajit Kembhavi Radha Chauhan Geetha Paul Janesh Kumar Ninan S. Philip
author_facet	Blesson George Anshul Assaiya Robin J. Roy Ajit Kembhavi Radha Chauhan Geetha Paul Janesh Kumar Ninan S. Philip
author_sort	Blesson George
title	CASSPER is a semantic segmentation-based particle picking algorithm for single-particle cryo-electron microscopy
title_short	CASSPER is a semantic segmentation-based particle picking algorithm for single-particle cryo-electron microscopy
title_full	CASSPER is a semantic segmentation-based particle picking algorithm for single-particle cryo-electron microscopy
title_fullStr	CASSPER is a semantic segmentation-based particle picking algorithm for single-particle cryo-electron microscopy
title_full_unstemmed	CASSPER is a semantic segmentation-based particle picking algorithm for single-particle cryo-electron microscopy
title_sort	cassper is a semantic segmentation-based particle picking algorithm for single-particle cryo-electron microscopy
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/ac44a665905d4502a0e70a0390fc2cd0
work_keys_str_mv	AT blessongeorge cassperisasemanticsegmentationbasedparticlepickingalgorithmforsingleparticlecryoelectronmicroscopy AT anshulassaiya cassperisasemanticsegmentationbasedparticlepickingalgorithmforsingleparticlecryoelectronmicroscopy AT robinjroy cassperisasemanticsegmentationbasedparticlepickingalgorithmforsingleparticlecryoelectronmicroscopy AT ajitkembhavi cassperisasemanticsegmentationbasedparticlepickingalgorithmforsingleparticlecryoelectronmicroscopy AT radhachauhan cassperisasemanticsegmentationbasedparticlepickingalgorithmforsingleparticlecryoelectronmicroscopy AT geethapaul cassperisasemanticsegmentationbasedparticlepickingalgorithmforsingleparticlecryoelectronmicroscopy AT janeshkumar cassperisasemanticsegmentationbasedparticlepickingalgorithmforsingleparticlecryoelectronmicroscopy AT ninansphilip cassperisasemanticsegmentationbasedparticlepickingalgorithmforsingleparticlecryoelectronmicroscopy
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CASSPER is a semantic segmentation-based particle picking algorithm for single-particle cryo-electron microscopy

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