INTRAVITREAL INTRODUCTION OF LUCENTIS AND TRANS-SCLERAL CYCLOPHOTOCOAGULATION IN THE TREATMENT OF NEOVASCULAR GLAUCOMA IN DIABETES MELLITUS

We analyzed the results of surgical treatment of 42 patients (42 eyes) with neovascular glaucoma on the background of proliferative diabetic retinopathy. Intravitreal injections of anti-VEGF-drugs allow to remove newly formed vessels in anterior chamber angle, to reduce intraocular pressure, to avoi...

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Autores principales: V. P. Fokin, S. V. Balalin, T. G. Yefremova, V. N. Potapova
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Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2016
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spelling oai:doaj.org-article:ac47b726307f443985fdfe17ce32a68c2021-11-23T06:14:36ZINTRAVITREAL INTRODUCTION OF LUCENTIS AND TRANS-SCLERAL CYCLOPHOTOCOAGULATION IN THE TREATMENT OF NEOVASCULAR GLAUCOMA IN DIABETES MELLITUS2541-94202587-959610.12737/23792https://doaj.org/article/ac47b726307f443985fdfe17ce32a68c2016-11-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/333https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596We analyzed the results of surgical treatment of 42 patients (42 eyes) with neovascular glaucoma on the background of proliferative diabetic retinopathy. Intravitreal injections of anti-VEGF-drugs allow to remove newly formed vessels in anterior chamber angle, to reduce intraocular pressure, to avoid complications in patients with neovascular glaucoma and the closed anterior chamber angle of the eye. The second stage of the treatment can be laser surgery. This approach helped to reduce intraocular pressure from 28.9 ± 0.9 to 18.5 ± 0.9 mmHg on the background of medical treatment (t > 2.0; p < 0.05). Visual acuity increased from 0.23 ± 0.07 to 0.44 ± 0.08 (t > 2.0; p < 0.05). In patients with NVG and closed anterior chamber angle of the eye, having aching glaucoma the use of laser surgery as the first stage of treatment allows to reduce intraocular pressure and to eliminate pain, and to apply intravitreal anti-VEGF-therapy as the second stage. The mean value of IOP decreased from 30.9 ± 1.2 to 20.1 ± 1.1 mmHg. During the year period, the second stage (intravitreal introduction of Lucentis) was performed in all patients. As a result, IOP was reduced to 17.5 ± 0.09 mmHg. Visual acuity increased from 0.18 ± 0.1 to 0.25 ± 0.07 (p > 0.05).V. P. FokinS. V. BalalinT. G. YefremovaV. N. PotapovaScientific Сentre for Family Health and Human Reproduction Problemsarticlediabetesneovascular glaucomaintravitreal anti-vegf-therapytrans-scleral cyclophotocoagulationScienceQRUActa Biomedica Scientifica, Vol 1, Iss 6, Pp 122-124 (2016)
institution DOAJ
collection DOAJ
language RU
topic diabetes
neovascular glaucoma
intravitreal anti-vegf-therapy
trans-scleral cyclophotocoagulation
Science
Q
spellingShingle diabetes
neovascular glaucoma
intravitreal anti-vegf-therapy
trans-scleral cyclophotocoagulation
Science
Q
V. P. Fokin
S. V. Balalin
T. G. Yefremova
V. N. Potapova
INTRAVITREAL INTRODUCTION OF LUCENTIS AND TRANS-SCLERAL CYCLOPHOTOCOAGULATION IN THE TREATMENT OF NEOVASCULAR GLAUCOMA IN DIABETES MELLITUS
description We analyzed the results of surgical treatment of 42 patients (42 eyes) with neovascular glaucoma on the background of proliferative diabetic retinopathy. Intravitreal injections of anti-VEGF-drugs allow to remove newly formed vessels in anterior chamber angle, to reduce intraocular pressure, to avoid complications in patients with neovascular glaucoma and the closed anterior chamber angle of the eye. The second stage of the treatment can be laser surgery. This approach helped to reduce intraocular pressure from 28.9 ± 0.9 to 18.5 ± 0.9 mmHg on the background of medical treatment (t > 2.0; p < 0.05). Visual acuity increased from 0.23 ± 0.07 to 0.44 ± 0.08 (t > 2.0; p < 0.05). In patients with NVG and closed anterior chamber angle of the eye, having aching glaucoma the use of laser surgery as the first stage of treatment allows to reduce intraocular pressure and to eliminate pain, and to apply intravitreal anti-VEGF-therapy as the second stage. The mean value of IOP decreased from 30.9 ± 1.2 to 20.1 ± 1.1 mmHg. During the year period, the second stage (intravitreal introduction of Lucentis) was performed in all patients. As a result, IOP was reduced to 17.5 ± 0.09 mmHg. Visual acuity increased from 0.18 ± 0.1 to 0.25 ± 0.07 (p > 0.05).
format article
author V. P. Fokin
S. V. Balalin
T. G. Yefremova
V. N. Potapova
author_facet V. P. Fokin
S. V. Balalin
T. G. Yefremova
V. N. Potapova
author_sort V. P. Fokin
title INTRAVITREAL INTRODUCTION OF LUCENTIS AND TRANS-SCLERAL CYCLOPHOTOCOAGULATION IN THE TREATMENT OF NEOVASCULAR GLAUCOMA IN DIABETES MELLITUS
title_short INTRAVITREAL INTRODUCTION OF LUCENTIS AND TRANS-SCLERAL CYCLOPHOTOCOAGULATION IN THE TREATMENT OF NEOVASCULAR GLAUCOMA IN DIABETES MELLITUS
title_full INTRAVITREAL INTRODUCTION OF LUCENTIS AND TRANS-SCLERAL CYCLOPHOTOCOAGULATION IN THE TREATMENT OF NEOVASCULAR GLAUCOMA IN DIABETES MELLITUS
title_fullStr INTRAVITREAL INTRODUCTION OF LUCENTIS AND TRANS-SCLERAL CYCLOPHOTOCOAGULATION IN THE TREATMENT OF NEOVASCULAR GLAUCOMA IN DIABETES MELLITUS
title_full_unstemmed INTRAVITREAL INTRODUCTION OF LUCENTIS AND TRANS-SCLERAL CYCLOPHOTOCOAGULATION IN THE TREATMENT OF NEOVASCULAR GLAUCOMA IN DIABETES MELLITUS
title_sort intravitreal introduction of lucentis and trans-scleral cyclophotocoagulation in the treatment of neovascular glaucoma in diabetes mellitus
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2016
url https://doaj.org/article/ac47b726307f443985fdfe17ce32a68c
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AT svbalalin intravitrealintroductionoflucentisandtransscleralcyclophotocoagulationinthetreatmentofneovascularglaucomaindiabetesmellitus
AT tgyefremova intravitrealintroductionoflucentisandtransscleralcyclophotocoagulationinthetreatmentofneovascularglaucomaindiabetesmellitus
AT vnpotapova intravitrealintroductionoflucentisandtransscleralcyclophotocoagulationinthetreatmentofneovascularglaucomaindiabetesmellitus
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