Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy

Iron is essential during pregnancy for embryo and placental development and maternal health. However, in this study using mouse models, the authors demonstrate that excess maternal iron causes adverse embryo outcomes in pregnancies with underlying systemic inflammation.

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Autores principales: Allison L. Fisher, Veena Sangkhae, Kamila Balušíková, Nicolaos J. Palaskas, Tomas Ganz, Elizabeta Nemeth
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/ac4d64ab15ae4a03b59b5d134970dd44
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Descripción
Sumario:Iron is essential during pregnancy for embryo and placental development and maternal health. However, in this study using mouse models, the authors demonstrate that excess maternal iron causes adverse embryo outcomes in pregnancies with underlying systemic inflammation.