Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy

Iron is essential during pregnancy for embryo and placental development and maternal health. However, in this study using mouse models, the authors demonstrate that excess maternal iron causes adverse embryo outcomes in pregnancies with underlying systemic inflammation.

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Autores principales:	Allison L. Fisher, Veena Sangkhae, Kamila Balušíková, Nicolaos J. Palaskas, Tomas Ganz, Elizabeta Nemeth
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ac4d64ab15ae4a03b59b5d134970dd44
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spelling	oai:doaj.org-article:ac4d64ab15ae4a03b59b5d134970dd442021-12-02T14:34:05ZIron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy10.1038/s41467-021-24333-z2041-1723https://doaj.org/article/ac4d64ab15ae4a03b59b5d134970dd442021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24333-zhttps://doaj.org/toc/2041-1723Iron is essential during pregnancy for embryo and placental development and maternal health. However, in this study using mouse models, the authors demonstrate that excess maternal iron causes adverse embryo outcomes in pregnancies with underlying systemic inflammation.Allison L. FisherVeena SangkhaeKamila BalušíkováNicolaos J. PalaskasTomas GanzElizabeta NemethNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Allison L. Fisher Veena Sangkhae Kamila Balušíková Nicolaos J. Palaskas Tomas Ganz Elizabeta Nemeth Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy
description	Iron is essential during pregnancy for embryo and placental development and maternal health. However, in this study using mouse models, the authors demonstrate that excess maternal iron causes adverse embryo outcomes in pregnancies with underlying systemic inflammation.
format	article
author	Allison L. Fisher Veena Sangkhae Kamila Balušíková Nicolaos J. Palaskas Tomas Ganz Elizabeta Nemeth
author_facet	Allison L. Fisher Veena Sangkhae Kamila Balušíková Nicolaos J. Palaskas Tomas Ganz Elizabeta Nemeth
author_sort	Allison L. Fisher
title	Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy
title_short	Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy
title_full	Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy
title_fullStr	Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy
title_full_unstemmed	Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy
title_sort	iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/ac4d64ab15ae4a03b59b5d134970dd44
work_keys_str_mv	AT allisonlfisher irondependentapoptosiscausesembryotoxicityininflamedandobesepregnancy AT veenasangkhae irondependentapoptosiscausesembryotoxicityininflamedandobesepregnancy AT kamilabalusikova irondependentapoptosiscausesembryotoxicityininflamedandobesepregnancy AT nicolaosjpalaskas irondependentapoptosiscausesembryotoxicityininflamedandobesepregnancy AT tomasganz irondependentapoptosiscausesembryotoxicityininflamedandobesepregnancy AT elizabetanemeth irondependentapoptosiscausesembryotoxicityininflamedandobesepregnancy
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Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy

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