PRR2, a pseudo-response regulator, promotes salicylic acid and camalexin accumulation during plant immunity

Abstract Calcium signalling mediated by Calmodulin (CaM) and calmodulin-like (CML) proteins is critical to plant immunity. CaM and CML regulate a wide range of target proteins and cellular responses. While many CaM-binding proteins have been identified, few have been characterized for their specific...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	C. Cheval, M. Perez, L. J. Leba, B. Ranty, A. Perochon, M. Reichelt, A. Mithöfer, E. Robe, C. Mazars, J. P. Galaud, D. Aldon
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/ac4e4375f2604b2eb338f8ad763c19c1
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:ac4e4375f2604b2eb338f8ad763c19c1
record_format	dspace
spelling	oai:doaj.org-article:ac4e4375f2604b2eb338f8ad763c19c12021-12-02T15:05:54ZPRR2, a pseudo-response regulator, promotes salicylic acid and camalexin accumulation during plant immunity10.1038/s41598-017-07535-82045-2322https://doaj.org/article/ac4e4375f2604b2eb338f8ad763c19c12017-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-07535-8https://doaj.org/toc/2045-2322Abstract Calcium signalling mediated by Calmodulin (CaM) and calmodulin-like (CML) proteins is critical to plant immunity. CaM and CML regulate a wide range of target proteins and cellular responses. While many CaM-binding proteins have been identified, few have been characterized for their specific role in plant immunity. Here, we report new data on the biological function of a CML-interacting partner, PRR2 (PSEUDO-RESPONSE REGULATOR 2), a plant specific transcription factor. Until now, the physiological relevance of PRR2 remained largely unknown. Using a reverse genetic strategy in A. thaliana, we identified PRR2 as a positive regulator of plant immunity. We propose that PRR2 contributes to salicylic acid (SA)-dependent responses when challenged with the phytopathogenic bacterium Pseudomonas syringae. PRR2 is transcriptionally upregulated by SA and P. syringae, enhances SA biosynthesis and SA signalling responses; e.g. in response to P. syringae, PRR2 induces the production of SA and the accumulation of the defence-related protein PR1. Moreover, PRR2 overexpressing lines exhibit an enhanced production of camalexin, a phytoalexin that confers enhanced resistance against pathogens. Together, these data reveal the importance of PRR2 in plant immune responses against P. syringae and suggest a novel function for this particular plant specific transcription factor in plant physiology.C. ChevalM. PerezL. J. LebaB. RantyA. PerochonM. ReicheltA. MithöferE. RobeC. MazarsJ. P. GalaudD. AldonNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q C. Cheval M. Perez L. J. Leba B. Ranty A. Perochon M. Reichelt A. Mithöfer E. Robe C. Mazars J. P. Galaud D. Aldon PRR2, a pseudo-response regulator, promotes salicylic acid and camalexin accumulation during plant immunity
description	Abstract Calcium signalling mediated by Calmodulin (CaM) and calmodulin-like (CML) proteins is critical to plant immunity. CaM and CML regulate a wide range of target proteins and cellular responses. While many CaM-binding proteins have been identified, few have been characterized for their specific role in plant immunity. Here, we report new data on the biological function of a CML-interacting partner, PRR2 (PSEUDO-RESPONSE REGULATOR 2), a plant specific transcription factor. Until now, the physiological relevance of PRR2 remained largely unknown. Using a reverse genetic strategy in A. thaliana, we identified PRR2 as a positive regulator of plant immunity. We propose that PRR2 contributes to salicylic acid (SA)-dependent responses when challenged with the phytopathogenic bacterium Pseudomonas syringae. PRR2 is transcriptionally upregulated by SA and P. syringae, enhances SA biosynthesis and SA signalling responses; e.g. in response to P. syringae, PRR2 induces the production of SA and the accumulation of the defence-related protein PR1. Moreover, PRR2 overexpressing lines exhibit an enhanced production of camalexin, a phytoalexin that confers enhanced resistance against pathogens. Together, these data reveal the importance of PRR2 in plant immune responses against P. syringae and suggest a novel function for this particular plant specific transcription factor in plant physiology.
format	article
author	C. Cheval M. Perez L. J. Leba B. Ranty A. Perochon M. Reichelt A. Mithöfer E. Robe C. Mazars J. P. Galaud D. Aldon
author_facet	C. Cheval M. Perez L. J. Leba B. Ranty A. Perochon M. Reichelt A. Mithöfer E. Robe C. Mazars J. P. Galaud D. Aldon
author_sort	C. Cheval
title	PRR2, a pseudo-response regulator, promotes salicylic acid and camalexin accumulation during plant immunity
title_short	PRR2, a pseudo-response regulator, promotes salicylic acid and camalexin accumulation during plant immunity
title_full	PRR2, a pseudo-response regulator, promotes salicylic acid and camalexin accumulation during plant immunity
title_fullStr	PRR2, a pseudo-response regulator, promotes salicylic acid and camalexin accumulation during plant immunity
title_full_unstemmed	PRR2, a pseudo-response regulator, promotes salicylic acid and camalexin accumulation during plant immunity
title_sort	prr2, a pseudo-response regulator, promotes salicylic acid and camalexin accumulation during plant immunity
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/ac4e4375f2604b2eb338f8ad763c19c1
work_keys_str_mv	AT ccheval prr2apseudoresponseregulatorpromotessalicylicacidandcamalexinaccumulationduringplantimmunity AT mperez prr2apseudoresponseregulatorpromotessalicylicacidandcamalexinaccumulationduringplantimmunity AT ljleba prr2apseudoresponseregulatorpromotessalicylicacidandcamalexinaccumulationduringplantimmunity AT branty prr2apseudoresponseregulatorpromotessalicylicacidandcamalexinaccumulationduringplantimmunity AT aperochon prr2apseudoresponseregulatorpromotessalicylicacidandcamalexinaccumulationduringplantimmunity AT mreichelt prr2apseudoresponseregulatorpromotessalicylicacidandcamalexinaccumulationduringplantimmunity AT amithofer prr2apseudoresponseregulatorpromotessalicylicacidandcamalexinaccumulationduringplantimmunity AT erobe prr2apseudoresponseregulatorpromotessalicylicacidandcamalexinaccumulationduringplantimmunity AT cmazars prr2apseudoresponseregulatorpromotessalicylicacidandcamalexinaccumulationduringplantimmunity AT jpgalaud prr2apseudoresponseregulatorpromotessalicylicacidandcamalexinaccumulationduringplantimmunity AT daldon prr2apseudoresponseregulatorpromotessalicylicacidandcamalexinaccumulationduringplantimmunity
_version_	1718388663761502208

PRR2, a pseudo-response regulator, promotes salicylic acid and camalexin accumulation during plant immunity

Ejemplares similares