Insights on autophagosome–lysosome tethering from structural and biochemical characterization of human autophagy factor EPG5
Nam and Cheung et al. describe the structural and biochemical characterization of human autophagy factor EPG5 that functions in autophagosome–lysosome tethering. They show that hEPG5 adopts an extended shepherd’s staff architecture, binds preferentially to GABARAP proteins, and is recruited to mitoc...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2021
|
| Subjects: | |
| Online Access: | https://doaj.org/article/ac50183ec2794e35b04eadd21d872781 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|