Human skeletal muscle plasmalemma alters its structure to change its Ca2+-handling following heavy-load resistance exercise

Heavy-load eccentric exercise causes an increase in cytoplasmic Ca2+ that can damage muscles. Here the authors show that the t-tubule system remodels into vacuoles that can sequester calcium from the cytoplasm and are not responsive to store-operated Ca2+ entry, thereby potentially protecting muscle...

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Bibliographic Details
Main Authors: Tanya R. Cully, Robyn M. Murphy, Llion Roberts, Truls Raastad, Robert G. Fassett, Jeff S. Coombes, Isuru D. Jayasinghe, Bradley S. Launikonis
Format: article
Language:EN
Published: Nature Portfolio 2017
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Q
Online Access:https://doaj.org/article/ac5dc5c88c904369b9a94eb7648f2c36
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