Assessing predicted HIV-1 replicative capacity in a clinical setting.

HIV-1 replicative capacity (RC) provides a measure of within-host fitness and is determined in the context of phenotypic drug resistance testing. However it is unclear how these in-vitro measurements relate to in-vivo processes. Here we assess RCs in a clinical setting by combining a previously publ...

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Main Authors: Roger D Kouyos, Viktor von Wyl, Trevor Hinkley, Christos J Petropoulos, Mojgan Haddad, Jeannette M Whitcomb, Jürg Böni, Sabine Yerly, Cristina Cellerai, Thomas Klimkait, Huldrych F Günthard, Sebastian Bonhoeffer, Swiss HIV Cohort Study
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
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Online Access:https://doaj.org/article/ac5e331eaef14db0a87440f062c39d55
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