Step-Specific Adaptation and Trade-Off over the Course of an Infection by GASP Mutation Small Colony Variants

Within-host evolution has been described in many bacterial diseases, and the genetic basis behind the adaptations has stimulated a lot of interest. Yet, the studied adaptations are generally focused on antibiotic resistance and rarely on the adaptation to the environment given by the host, and the...

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Autores principales:	Christian Faucher, Vincent Mazana, Marion Kardacz, Nathalie Parthuisot, Jean-Baptiste Ferdy, David Duneau
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/ac62b47caf984c6b9d1601eef549f7b1
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spelling	oai:doaj.org-article:ac62b47caf984c6b9d1601eef549f7b12021-11-03T18:15:37ZStep-Specific Adaptation and Trade-Off over the Course of an Infection by GASP Mutation Small Colony Variants2161-21292150-751110.1128/mBio.01399-20https://doaj.org/article/ac62b47caf984c6b9d1601eef549f7b12021-02-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.01399-20https://doaj.org/toc/2161-2129https://doaj.org/toc/2150-7511 Within-host evolution has been described in many bacterial diseases, and the genetic basis behind the adaptations has stimulated a lot of interest. Yet, the studied adaptations are generally focused on antibiotic resistance and rarely on the adaptation to the environment given by the host, and the potential trade-offs hindering adaptations to each step of the infection are rarely considered.Christian FaucherVincent MazanaMarion KardaczNathalie ParthuisotJean-Baptiste FerdyDavid DuneauAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 1 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Christian Faucher Vincent Mazana Marion Kardacz Nathalie Parthuisot Jean-Baptiste Ferdy David Duneau Step-Specific Adaptation and Trade-Off over the Course of an Infection by GASP Mutation Small Colony Variants
description	Within-host evolution has been described in many bacterial diseases, and the genetic basis behind the adaptations has stimulated a lot of interest. Yet, the studied adaptations are generally focused on antibiotic resistance and rarely on the adaptation to the environment given by the host, and the potential trade-offs hindering adaptations to each step of the infection are rarely considered.
format	article
author	Christian Faucher Vincent Mazana Marion Kardacz Nathalie Parthuisot Jean-Baptiste Ferdy David Duneau
author_facet	Christian Faucher Vincent Mazana Marion Kardacz Nathalie Parthuisot Jean-Baptiste Ferdy David Duneau
author_sort	Christian Faucher
title	Step-Specific Adaptation and Trade-Off over the Course of an Infection by GASP Mutation Small Colony Variants
title_short	Step-Specific Adaptation and Trade-Off over the Course of an Infection by GASP Mutation Small Colony Variants
title_full	Step-Specific Adaptation and Trade-Off over the Course of an Infection by GASP Mutation Small Colony Variants
title_fullStr	Step-Specific Adaptation and Trade-Off over the Course of an Infection by GASP Mutation Small Colony Variants
title_full_unstemmed	Step-Specific Adaptation and Trade-Off over the Course of an Infection by GASP Mutation Small Colony Variants
title_sort	step-specific adaptation and trade-off over the course of an infection by gasp mutation small colony variants
publisher	American Society for Microbiology
publishDate	2021
url	https://doaj.org/article/ac62b47caf984c6b9d1601eef549f7b1
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Step-Specific Adaptation and Trade-Off over the Course of an Infection by GASP Mutation Small Colony Variants

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