Non-quaternary oximes detoxify nerve agents and reactivate nerve agent-inhibited human butyrylcholinesterase

Amitai et al. identified 4 potential small molecule antidotes toward nerve agents poisoning by high-throughput-screening of over 150,000 compounds. Unique non-quaternary oximes represent new potential antidotes for future development as they detoxified nerve agents and also reactivated nerve agent-i...

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Autores principales: Gabriel Amitai, Alexander Plotnikov, Shira Chapman, Shlomi Lazar, Rellie Gez, Dan Loewenthal, Khriesto A. Shurrush, Galit Cohen, Leonardo J. Solmesky, Haim Barr, Alan J. Russell
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/ac7bf1ed74314e84bce92d5d5c901cca
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