Improvement in Cardiometabolic Risk Factors During Smoking Cessation Treatment in Patients with Type 2 Diabetes: A Retrospective Cohort Study

Hsin-Ju Chen,1 Wei-Hsin Huang,1 Hsin-Lung Chan,1 Lee-Ching Hwang1,2 1Department of Family Medicine, Mackay Memorial Hospital, Taipei, Taiwan; 2Department of Medicine, Mackay Medical College, New Taipei City, TaiwanCorrespondence: Lee-Ching HwangDepartment of Family Medicine, Mackay Memorial Hospital...

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Autores principales:	Chen HJ, Huang WH, Chan HL, Hwang LC
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	cardiometabolic risk factor body weight glycemic control smoking cessation type 2 diabetes Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/ac81441e14e84a1686248364a4beb671
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spelling	oai:doaj.org-article:ac81441e14e84a1686248364a4beb6712021-12-02T14:27:54ZImprovement in Cardiometabolic Risk Factors During Smoking Cessation Treatment in Patients with Type 2 Diabetes: A Retrospective Cohort Study1178-7007https://doaj.org/article/ac81441e14e84a1686248364a4beb6712021-04-01T00:00:00Zhttps://www.dovepress.com/improvement-in-cardiometabolic-risk-factors-during-smoking-cessation-t-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Hsin-Ju Chen,1 Wei-Hsin Huang,1 Hsin-Lung Chan,1 Lee-Ching Hwang1,2 1Department of Family Medicine, Mackay Memorial Hospital, Taipei, Taiwan; 2Department of Medicine, Mackay Medical College, New Taipei City, TaiwanCorrespondence: Lee-Ching HwangDepartment of Family Medicine, Mackay Memorial Hospital, No. 92, Sec. 2, Zhongshan North Road, Taipei City, 10449, TaiwanTel +886 2 2543 3535 #2136Fax +886 2 2521 3847Email hlc@mmh.org.twPurpose: Smoking cessation reduces morbidity and mortality of cardiovascular diseases. The purpose of this study was to evaluate the effect during smoking cessation treatment on glycemic control and cardiometabolic risk factors, including blood pressure and lipid levels, in patients with type 2 diabetes.Patients and Methods: This retrospective cohort study included patients with type 2 diabetes who participated in a smoking cessation program, which comprised health education and medication prescription at an outpatient clinic in combination with a 3-month follow-up by phone. Data on patient background characteristics, cardiometabolic factors, smoking status, body weight, and body mass index before and after the program were collected for analysis.Results: The analysis included 241 participants with an average age of 58.6 ± 10.6 years. The rate of successful cessation at three months was 34.0%. Compared with the baseline levels, there were significant decreases in the levels of fasting plasma glucose (10.0 ± 46.8 mg/dL, P = 0.001), HbA1c (0.3 ± 1.4%, P = 0.004), systolic blood pressure (4.6 ± 17.5 mmHg, P < 0.001), diastolic blood pressure (2.9 ± 11.3 mmHg, P < 0.001), and total cholesterol (7.9 ± 42.8 mg/dL, P = 0.020) after participation in the smoking cessation program while there was no significant difference in body weight (0.1 ± 1.2 kg, P = 0.444). After adjustment for covariates, the decreases in HbA1c and total cholesterol levels were significantly better in younger participants and higher baseline nicotine dependence scores were associated with decreases in the levels of blood pressure, fasting plasma glucose, and triglycerides. However, the decrease in smoking amount was not associated with the changes in cardiometabolic factors.Conclusion: Participation in a smoking cessation program was associated with improvements in glycemic control and cardiometabolic risk factors in patients with type 2 diabetes. The observed improvements were associated with participation in the program but not with the decrease in smoking amount.Keywords: cardiometabolic risk factor, body weight, glycemic control, smoking cessation, type 2 diabetesChen HJHuang WHChan HLHwang LCDove Medical Pressarticlecardiometabolic risk factorbody weightglycemic controlsmoking cessationtype 2 diabetesSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 14, Pp 1695-1702 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cardiometabolic risk factor body weight glycemic control smoking cessation type 2 diabetes Specialties of internal medicine RC581-951
spellingShingle	cardiometabolic risk factor body weight glycemic control smoking cessation type 2 diabetes Specialties of internal medicine RC581-951 Chen HJ Huang WH Chan HL Hwang LC Improvement in Cardiometabolic Risk Factors During Smoking Cessation Treatment in Patients with Type 2 Diabetes: A Retrospective Cohort Study
description	Hsin-Ju Chen,1 Wei-Hsin Huang,1 Hsin-Lung Chan,1 Lee-Ching Hwang1,2 1Department of Family Medicine, Mackay Memorial Hospital, Taipei, Taiwan; 2Department of Medicine, Mackay Medical College, New Taipei City, TaiwanCorrespondence: Lee-Ching HwangDepartment of Family Medicine, Mackay Memorial Hospital, No. 92, Sec. 2, Zhongshan North Road, Taipei City, 10449, TaiwanTel +886 2 2543 3535 #2136Fax +886 2 2521 3847Email hlc@mmh.org.twPurpose: Smoking cessation reduces morbidity and mortality of cardiovascular diseases. The purpose of this study was to evaluate the effect during smoking cessation treatment on glycemic control and cardiometabolic risk factors, including blood pressure and lipid levels, in patients with type 2 diabetes.Patients and Methods: This retrospective cohort study included patients with type 2 diabetes who participated in a smoking cessation program, which comprised health education and medication prescription at an outpatient clinic in combination with a 3-month follow-up by phone. Data on patient background characteristics, cardiometabolic factors, smoking status, body weight, and body mass index before and after the program were collected for analysis.Results: The analysis included 241 participants with an average age of 58.6 ± 10.6 years. The rate of successful cessation at three months was 34.0%. Compared with the baseline levels, there were significant decreases in the levels of fasting plasma glucose (10.0 ± 46.8 mg/dL, P = 0.001), HbA1c (0.3 ± 1.4%, P = 0.004), systolic blood pressure (4.6 ± 17.5 mmHg, P < 0.001), diastolic blood pressure (2.9 ± 11.3 mmHg, P < 0.001), and total cholesterol (7.9 ± 42.8 mg/dL, P = 0.020) after participation in the smoking cessation program while there was no significant difference in body weight (0.1 ± 1.2 kg, P = 0.444). After adjustment for covariates, the decreases in HbA1c and total cholesterol levels were significantly better in younger participants and higher baseline nicotine dependence scores were associated with decreases in the levels of blood pressure, fasting plasma glucose, and triglycerides. However, the decrease in smoking amount was not associated with the changes in cardiometabolic factors.Conclusion: Participation in a smoking cessation program was associated with improvements in glycemic control and cardiometabolic risk factors in patients with type 2 diabetes. The observed improvements were associated with participation in the program but not with the decrease in smoking amount.Keywords: cardiometabolic risk factor, body weight, glycemic control, smoking cessation, type 2 diabetes
format	article
author	Chen HJ Huang WH Chan HL Hwang LC
author_facet	Chen HJ Huang WH Chan HL Hwang LC
author_sort	Chen HJ
title	Improvement in Cardiometabolic Risk Factors During Smoking Cessation Treatment in Patients with Type 2 Diabetes: A Retrospective Cohort Study
title_short	Improvement in Cardiometabolic Risk Factors During Smoking Cessation Treatment in Patients with Type 2 Diabetes: A Retrospective Cohort Study
title_full	Improvement in Cardiometabolic Risk Factors During Smoking Cessation Treatment in Patients with Type 2 Diabetes: A Retrospective Cohort Study
title_fullStr	Improvement in Cardiometabolic Risk Factors During Smoking Cessation Treatment in Patients with Type 2 Diabetes: A Retrospective Cohort Study
title_full_unstemmed	Improvement in Cardiometabolic Risk Factors During Smoking Cessation Treatment in Patients with Type 2 Diabetes: A Retrospective Cohort Study
title_sort	improvement in cardiometabolic risk factors during smoking cessation treatment in patients with type 2 diabetes: a retrospective cohort study
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/ac81441e14e84a1686248364a4beb671
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Improvement in Cardiometabolic Risk Factors During Smoking Cessation Treatment in Patients with Type 2 Diabetes: A Retrospective Cohort Study

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