Core Fucosylation of Maternal Milk N-Glycan Evokes B Cell Activation by Selectively Promoting the <sc>l</sc>-Fucose Metabolism of Gut <italic toggle="yes">Bifidobacterium</italic> spp. and <italic toggle="yes">Lactobacillus</italic> spp

Core Fucosylation of Maternal Milk N-Glycan Evokes B Cell Activation by Selectively Promoting the <sc>l</sc>-Fucose Metabolism of Gut <italic toggle="yes">Bifidobacterium</italic> spp. and <italic toggle="yes">Lactobacillus</italic> spp

ABSTRACT The maternal milk glycobiome is crucial for shaping the gut microbiota of infants. Although high core fucosylation catalyzed by fucosyltransferase 8 (Fut8) is a general feature of human milk glycoproteins, its role in the formation of a healthy microbiota has not been evaluated. In this stu...

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Bibliographic Details
Main Authors: Ming Li, Yaqiang Bai, Jiaorui Zhou, Wei Huang, Jingyu Yan, Jia Tao, Qingjie Fan, Yang Liu, Di Mei, Qiulong Yan, Jieli Yuan, Patrice Malard, Zhongfu Wang, Jianguo Gu, Naoyuki Tanigchi, Wenzhe Li
Format: article
Language:EN
Published: American Society for Microbiology 2019
Subjects:
B cells
Bifidobacterium
Lactobacillus
core fucosylation
infants
milk N-glycan
Microbiology
QR1-502
Online Access:https://doaj.org/article/ac86f877e6264314a9f7f9c1beadf892
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