FIERY1 promotes microRNA accumulation by suppressing rRNA-derived small interfering RNAs in Arabidopsis

Arabidopsis AGO1 binds both microRNA (miRNA) and endogenous small interfering RNA (siRNA). Here the authors show that 5′−3′ RNA degradation suppresses siRNA biogenesis from ribosomal RNA to prevent overloading of AGO1 with ribosomal siRNA and maintain miRNA-directed post translational gene silencing...

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Autores principales: Chenjiang You, Wenrong He, Runlai Hang, Cuiju Zhang, Xiaofeng Cao, Hongwei Guo, Xuemei Chen, Jie Cui, Beixin Mo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/ac91ac5da5134d138496b718baa4a6f5
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spelling oai:doaj.org-article:ac91ac5da5134d138496b718baa4a6f52021-12-02T17:01:53ZFIERY1 promotes microRNA accumulation by suppressing rRNA-derived small interfering RNAs in Arabidopsis10.1038/s41467-019-12379-z2041-1723https://doaj.org/article/ac91ac5da5134d138496b718baa4a6f52019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12379-zhttps://doaj.org/toc/2041-1723Arabidopsis AGO1 binds both microRNA (miRNA) and endogenous small interfering RNA (siRNA). Here the authors show that 5′−3′ RNA degradation suppresses siRNA biogenesis from ribosomal RNA to prevent overloading of AGO1 with ribosomal siRNA and maintain miRNA-directed post translational gene silencing.Chenjiang YouWenrong HeRunlai HangCuiju ZhangXiaofeng CaoHongwei GuoXuemei ChenJie CuiBeixin MoNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Chenjiang You
Wenrong He
Runlai Hang
Cuiju Zhang
Xiaofeng Cao
Hongwei Guo
Xuemei Chen
Jie Cui
Beixin Mo
FIERY1 promotes microRNA accumulation by suppressing rRNA-derived small interfering RNAs in Arabidopsis
description Arabidopsis AGO1 binds both microRNA (miRNA) and endogenous small interfering RNA (siRNA). Here the authors show that 5′−3′ RNA degradation suppresses siRNA biogenesis from ribosomal RNA to prevent overloading of AGO1 with ribosomal siRNA and maintain miRNA-directed post translational gene silencing.
format article
author Chenjiang You
Wenrong He
Runlai Hang
Cuiju Zhang
Xiaofeng Cao
Hongwei Guo
Xuemei Chen
Jie Cui
Beixin Mo
author_facet Chenjiang You
Wenrong He
Runlai Hang
Cuiju Zhang
Xiaofeng Cao
Hongwei Guo
Xuemei Chen
Jie Cui
Beixin Mo
author_sort Chenjiang You
title FIERY1 promotes microRNA accumulation by suppressing rRNA-derived small interfering RNAs in Arabidopsis
title_short FIERY1 promotes microRNA accumulation by suppressing rRNA-derived small interfering RNAs in Arabidopsis
title_full FIERY1 promotes microRNA accumulation by suppressing rRNA-derived small interfering RNAs in Arabidopsis
title_fullStr FIERY1 promotes microRNA accumulation by suppressing rRNA-derived small interfering RNAs in Arabidopsis
title_full_unstemmed FIERY1 promotes microRNA accumulation by suppressing rRNA-derived small interfering RNAs in Arabidopsis
title_sort fiery1 promotes microrna accumulation by suppressing rrna-derived small interfering rnas in arabidopsis
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/ac91ac5da5134d138496b718baa4a6f5
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