A role for LHC1 in higher order structure and complement binding of the Cryptococcus neoformans capsule.
Polysaccharide capsules are important virulence factors for many microbial pathogens including the opportunistic fungus Cryptococcus neoformans. In the present study, we demonstrate an unusual role for a secreted lactonohydrolase of C. neoformans, LHC1 in capsular higher order structure. Analysis of...
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Main Authors: | Yoon-Dong Park, Soowan Shin, John Panepinto, Jeanie Ramos, Jin Qiu, Susana Frases, Patricia Albuquerque, Radames J B Cordero, Nannan Zhang, Uwe Himmelreich, David Beenhouwer, John E Bennett, Arturo Casadevall, Peter R Williamson |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2014
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Online Access: | https://doaj.org/article/ac9671a3a9724e458af31c7416bab8f3 |
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