CLINICAL AND IMMUNOLOGICAL CHARACTERISTICS OF PATIENTS WITH HERPES INFECTIONS OF VARYING SEVERITY

The peculiarities of clinical signs, immune and interferon status in 180 patients with laboratory confirmed infection of varying severity, caused by herpes simplex virus (VSHI) have been studied. It was determined that frequency of bacterial infections is increased in patients with more severe clini...

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Autores principales:	T. M. Lyuboshenko, T. I. Dolgikh
Formato:	article
Lenguaje:	RU
Publicado:	Sankt-Peterburg : NIIÈM imeni Pastera 2015
Materias:	herpesvirus infection clinical manifestations diagnosis immune profile course severity Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/aca9890d6a184d969b3ddae330fab05e
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spelling	oai:doaj.org-article:aca9890d6a184d969b3ddae330fab05e2021-11-22T07:09:47ZCLINICAL AND IMMUNOLOGICAL CHARACTERISTICS OF PATIENTS WITH HERPES INFECTIONS OF VARYING SEVERITY2220-76192313-739810.15789/2220-7619-2014-4-359-364https://doaj.org/article/aca9890d6a184d969b3ddae330fab05e2015-02-01T00:00:00Zhttps://www.iimmun.ru/iimm/article/view/247https://doaj.org/toc/2220-7619https://doaj.org/toc/2313-7398The peculiarities of clinical signs, immune and interferon status in 180 patients with laboratory confirmed infection of varying severity, caused by herpes simplex virus (VSHI) have been studied. It was determined that frequency of bacterial infections is increased in patients with more severe clinical forms of VSHI. In patients with mild course furunculosis was more often detected than in other groups. In patients with moderate course of VSHI vaginal candidiasis was more common. In patients with severe VSHI course the combination of labial and genital herpes as well as infection caused by the human papilloma virus were more prevalent. In case of severe infection occurred an increased frequency of dysbiosis, fatigue, low grade temperature, iron deficiency anemia and malignancies. The highest frequency of allergic reactions is observed in patients with moderate course of VSHI. The autoimmune syndrome manifestations were not depend on the severity of VSHI. The degree of reduction of cell immunity and disorders in the system of interferon were closely related to severity of VSHI course.T. M. LyuboshenkoT. I. DolgikhSankt-Peterburg : NIIÈM imeni Pasteraarticleherpesvirus infectionclinical manifestationsdiagnosisimmune profilecourse severityInfectious and parasitic diseasesRC109-216RUInfekciâ i Immunitet, Vol 4, Iss 4, Pp 359-364 (2015)
institution	DOAJ
collection	DOAJ
language	RU
topic	herpesvirus infection clinical manifestations diagnosis immune profile course severity Infectious and parasitic diseases RC109-216
spellingShingle	herpesvirus infection clinical manifestations diagnosis immune profile course severity Infectious and parasitic diseases RC109-216 T. M. Lyuboshenko T. I. Dolgikh CLINICAL AND IMMUNOLOGICAL CHARACTERISTICS OF PATIENTS WITH HERPES INFECTIONS OF VARYING SEVERITY
description	The peculiarities of clinical signs, immune and interferon status in 180 patients with laboratory confirmed infection of varying severity, caused by herpes simplex virus (VSHI) have been studied. It was determined that frequency of bacterial infections is increased in patients with more severe clinical forms of VSHI. In patients with mild course furunculosis was more often detected than in other groups. In patients with moderate course of VSHI vaginal candidiasis was more common. In patients with severe VSHI course the combination of labial and genital herpes as well as infection caused by the human papilloma virus were more prevalent. In case of severe infection occurred an increased frequency of dysbiosis, fatigue, low grade temperature, iron deficiency anemia and malignancies. The highest frequency of allergic reactions is observed in patients with moderate course of VSHI. The autoimmune syndrome manifestations were not depend on the severity of VSHI. The degree of reduction of cell immunity and disorders in the system of interferon were closely related to severity of VSHI course.
format	article
author	T. M. Lyuboshenko T. I. Dolgikh
author_facet	T. M. Lyuboshenko T. I. Dolgikh
author_sort	T. M. Lyuboshenko
title	CLINICAL AND IMMUNOLOGICAL CHARACTERISTICS OF PATIENTS WITH HERPES INFECTIONS OF VARYING SEVERITY
title_short	CLINICAL AND IMMUNOLOGICAL CHARACTERISTICS OF PATIENTS WITH HERPES INFECTIONS OF VARYING SEVERITY
title_full	CLINICAL AND IMMUNOLOGICAL CHARACTERISTICS OF PATIENTS WITH HERPES INFECTIONS OF VARYING SEVERITY
title_fullStr	CLINICAL AND IMMUNOLOGICAL CHARACTERISTICS OF PATIENTS WITH HERPES INFECTIONS OF VARYING SEVERITY
title_full_unstemmed	CLINICAL AND IMMUNOLOGICAL CHARACTERISTICS OF PATIENTS WITH HERPES INFECTIONS OF VARYING SEVERITY
title_sort	clinical and immunological characteristics of patients with herpes infections of varying severity
publisher	Sankt-Peterburg : NIIÈM imeni Pastera
publishDate	2015
url	https://doaj.org/article/aca9890d6a184d969b3ddae330fab05e
work_keys_str_mv	AT tmlyuboshenko clinicalandimmunologicalcharacteristicsofpatientswithherpesinfectionsofvaryingseverity AT tidolgikh clinicalandimmunologicalcharacteristicsofpatientswithherpesinfectionsofvaryingseverity
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CLINICAL AND IMMUNOLOGICAL CHARACTERISTICS OF PATIENTS WITH HERPES INFECTIONS OF VARYING SEVERITY

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