Engineering species-like barriers to sexual reproduction

Genetic isolation of a genetically modified organism represents a useful strategy for biocontainment. Here the authors use dCas9-VP64-driven gene expression to construct a ‘species-like’ barrier to reproduction between two otherwise compatible populations.

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Detalles Bibliográficos
Autores principales: Maciej Maselko, Stephen C. Heinsch, Jeremy M. Chacón, William R. Harcombe, Michael J. Smanski
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/acabf95d0c834ff197052d558dcbfeae
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Descripción
Sumario:Genetic isolation of a genetically modified organism represents a useful strategy for biocontainment. Here the authors use dCas9-VP64-driven gene expression to construct a ‘species-like’ barrier to reproduction between two otherwise compatible populations.