Engineering species-like barriers to sexual reproduction

Genetic isolation of a genetically modified organism represents a useful strategy for biocontainment. Here the authors use dCas9-VP64-driven gene expression to construct a ‘species-like’ barrier to reproduction between two otherwise compatible populations.

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Autores principales: Maciej Maselko, Stephen C. Heinsch, Jeremy M. Chacón, William R. Harcombe, Michael J. Smanski
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/acabf95d0c834ff197052d558dcbfeae
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spelling oai:doaj.org-article:acabf95d0c834ff197052d558dcbfeae2021-12-02T14:41:21ZEngineering species-like barriers to sexual reproduction10.1038/s41467-017-01007-32041-1723https://doaj.org/article/acabf95d0c834ff197052d558dcbfeae2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01007-3https://doaj.org/toc/2041-1723Genetic isolation of a genetically modified organism represents a useful strategy for biocontainment. Here the authors use dCas9-VP64-driven gene expression to construct a ‘species-like’ barrier to reproduction between two otherwise compatible populations.Maciej MaselkoStephen C. HeinschJeremy M. ChacónWilliam R. HarcombeMichael J. SmanskiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Maciej Maselko
Stephen C. Heinsch
Jeremy M. Chacón
William R. Harcombe
Michael J. Smanski
Engineering species-like barriers to sexual reproduction
description Genetic isolation of a genetically modified organism represents a useful strategy for biocontainment. Here the authors use dCas9-VP64-driven gene expression to construct a ‘species-like’ barrier to reproduction between two otherwise compatible populations.
format article
author Maciej Maselko
Stephen C. Heinsch
Jeremy M. Chacón
William R. Harcombe
Michael J. Smanski
author_facet Maciej Maselko
Stephen C. Heinsch
Jeremy M. Chacón
William R. Harcombe
Michael J. Smanski
author_sort Maciej Maselko
title Engineering species-like barriers to sexual reproduction
title_short Engineering species-like barriers to sexual reproduction
title_full Engineering species-like barriers to sexual reproduction
title_fullStr Engineering species-like barriers to sexual reproduction
title_full_unstemmed Engineering species-like barriers to sexual reproduction
title_sort engineering species-like barriers to sexual reproduction
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/acabf95d0c834ff197052d558dcbfeae
work_keys_str_mv AT maciejmaselko engineeringspecieslikebarrierstosexualreproduction
AT stephencheinsch engineeringspecieslikebarrierstosexualreproduction
AT jeremymchacon engineeringspecieslikebarrierstosexualreproduction
AT williamrharcombe engineeringspecieslikebarrierstosexualreproduction
AT michaeljsmanski engineeringspecieslikebarrierstosexualreproduction
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