Engineering species-like barriers to sexual reproduction
Genetic isolation of a genetically modified organism represents a useful strategy for biocontainment. Here the authors use dCas9-VP64-driven gene expression to construct a ‘species-like’ barrier to reproduction between two otherwise compatible populations.
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Nature Portfolio
2017
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oai:doaj.org-article:acabf95d0c834ff197052d558dcbfeae2021-12-02T14:41:21ZEngineering species-like barriers to sexual reproduction10.1038/s41467-017-01007-32041-1723https://doaj.org/article/acabf95d0c834ff197052d558dcbfeae2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01007-3https://doaj.org/toc/2041-1723Genetic isolation of a genetically modified organism represents a useful strategy for biocontainment. Here the authors use dCas9-VP64-driven gene expression to construct a ‘species-like’ barrier to reproduction between two otherwise compatible populations.Maciej MaselkoStephen C. HeinschJeremy M. ChacónWilliam R. HarcombeMichael J. SmanskiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-7 (2017) |
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Science Q |
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Science Q Maciej Maselko Stephen C. Heinsch Jeremy M. Chacón William R. Harcombe Michael J. Smanski Engineering species-like barriers to sexual reproduction |
description |
Genetic isolation of a genetically modified organism represents a useful strategy for biocontainment. Here the authors use dCas9-VP64-driven gene expression to construct a ‘species-like’ barrier to reproduction between two otherwise compatible populations. |
format |
article |
author |
Maciej Maselko Stephen C. Heinsch Jeremy M. Chacón William R. Harcombe Michael J. Smanski |
author_facet |
Maciej Maselko Stephen C. Heinsch Jeremy M. Chacón William R. Harcombe Michael J. Smanski |
author_sort |
Maciej Maselko |
title |
Engineering species-like barriers to sexual reproduction |
title_short |
Engineering species-like barriers to sexual reproduction |
title_full |
Engineering species-like barriers to sexual reproduction |
title_fullStr |
Engineering species-like barriers to sexual reproduction |
title_full_unstemmed |
Engineering species-like barriers to sexual reproduction |
title_sort |
engineering species-like barriers to sexual reproduction |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/acabf95d0c834ff197052d558dcbfeae |
work_keys_str_mv |
AT maciejmaselko engineeringspecieslikebarrierstosexualreproduction AT stephencheinsch engineeringspecieslikebarrierstosexualreproduction AT jeremymchacon engineeringspecieslikebarrierstosexualreproduction AT williamrharcombe engineeringspecieslikebarrierstosexualreproduction AT michaeljsmanski engineeringspecieslikebarrierstosexualreproduction |
_version_ |
1718389953014005760 |