The RepID–CRL4 ubiquitin ligase complex regulates metaphase to anaphase transition via BUB3 degradation

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The RepID–CRL4 ubiquitin ligase complex regulates metaphase to anaphase transition via BUB3 degradation

The spindle assembly checkpoint (SAC) safeguards chromosome segregation by regulating the anaphase promoting complex/cyclosome (APC/C), allowing chromosomes to correctly attach to mitotic spindles. Here the authors reveal a role for Cullin–RING ubiquitin ligase complex 4 (CRL4) in regulating metapha...

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Auteurs principaux:	Sang-Min Jang, Jenny F. Nathans, Haiqing Fu, Christophe E. Redon, Lisa M. Jenkins, Bhushan L. Thakur, Lőrinc S. Pongor, Adrian M. Baris, Jacob M. Gross, Maura J. OʹNeill, Fred E. Indig, Steven D. Cappell, Mirit I. Aladjem
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2020
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/acb64edefaf545c091ce4db99899a6a3
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

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