Mitochondrial adaptor TRAK2 activates and functionally links opposing kinesin and dynein motors

Mitochondrial transport toward both the plus- and minus-ends of microtubules is mediated by motor proteins linked to mitochondria by TRAK adaptor proteins. Here the authors investigate the role of TRAK2 as a bidirectional motor adaptor, and propose a model where TRAK2 coordinates the activities of o...

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Auteurs principaux: Adam R. Fenton, Thomas A. Jongens, Erika L. F. Holzbaur
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/acb6e48bd1c84d51b3fcfa57aca067cf
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